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Thiazole is a heterocyclic organic compound that has a fivemembered molecular ring structure with molecular formula C3H3NS. It possesses both an electron-donating group (-S-) and an electron-accepting group (C]N). It is a stable heterocyclic compound and has Bird IA value of 79. Thiazole is aromatic on the basis of delocalization of a lone pair of electrons from the sulphur atom completing the desirable 6 p electrons to fulfil Huckel's rule. The thiazole ring is present in many natural and synthetic products with a broad range of biological activities for example, thiazole containing vitamin B1 (thiamine) helps in the normal functioning of the nervous system by its role in the synthesis of acetylcholine [1]. Thiazole ring is highly reactive due to the presence of an acidic proton at C-2 and has emerged as an important synthon to generate variety of NCEs (New Chemical Entities). Diverse modifications of the thiazole ring at various positions led to a variety of novel compounds with wide spectrum of pharmacological activities such as antioxidant, antibacterial, antifungal, antitubercular, diuretic, anti-inflammatory and anticancer activities |
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武汉一心一译 
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jdy1947: 金币+50, 翻译EPI+1, ★★★★★最佳答案 2016-05-03 08:11:31
jdy1947: 金币+50, 翻译EPI+1, ★★★★★最佳答案 2016-05-03 08:11:31
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Thiazole is a heterocyclic organic compound that has a fivemembered molecular ring structure with molecular formula C3H3NS. It possesses both an electron-donating group (-S-) and an electron-accepting group (C]N). 噻唑是一种五节分子环结构有机化合物，分子式为C3H3NS。 它既有供电子基团 (-S-)也有电子接受基团(C]N)。 It is a stable heterocyclic compound and has Bird IA value of 79. Thiazole is aromatic on the basis of delocalization of a lone pair of electrons from the sulphur atom completing the desirable 6 p electrons to fulfil Huckel's rule. 作为一种稳定的杂环化合物，噻唑的 Bird IA value（相对原子质量？）为79. 噻唑是一种芳香族化合物， 在对硫原子的一对孤对电子进行离域作用的基础上，完成外层硫原子6个电子，从而满足休克尔规则。 The thiazole ring is present in many natural and synthetic products with a broad range of biological activities for example, thiazole containing vitamin B1 (thiamine) helps in the normal functioning of the nervous system by its role in the synthesis of acetylcholine [1]. 许多自然和合成产品都含有噻唑环，其涉及的生物活动广泛例如还有维他命B1的噻唑（硫胺素），因其能够合成乙酰胆碱，能够保证神经系统的正常功能。 Thiazole ring is highly reactive due to the presence of an acidic proton at C-2 and has emerged as an important synthon to generate variety of NCEs (New Chemical Entities). 因为有一个酸性质子存在于C-2上，噻唑环具有高反应性，同时作为一种重要的合成子，它可以激发各种新化学实体的生成。 Diverse modifications of the thiazole ring at various positions led to a variety of novel compounds with wide spectrum of pharmacological activities such as antioxidant, antibacterial, antifungal, antitubercular, diuretic, anti-inflammatory and anticancer activities 对噻唑环不同部位进行改性处理，可以合成具有各种药理活性的新型化合物：例如抗氧化剂，抗菌剂，抗真菌剂，抗结核剂，利尿剂，消炎药，抗癌药物。 |
2楼2016-05-02 19:32:17