| 查看: 808 | 回复: 4 | ||
| 本帖产生 1 个 翻译EPI ，点击这里进行查看 | ||
[求助]
求翻译，求帮忙。。。。
|
||
|
The outer edges of the Lzr gene cluster were defined based on comparisons to the BE-54017 and cladoniamide gene clusters and a BLAST analysis of genes surrounding the core indolotryptoline biosynthesis genes (Fig. 3A). The biosynthesis of indolotryptolines is well-characterized, making it possible to predict the function of most genes in the Lzr gene cluster (32). The four key stages of indolotryptoline biosynthesis involve dimerization of oxo-tryptophan to form a chromopyrrolic acid, oxidative aryl–aryl coupling to form an indolocarbazole, “flipping” of one of the indole rings to form an indolotryptoline, and tailoring to generate the final product. The Lzr gene cluster is predicted to contain seven transcriptional units controlled by three bidirectional (P1, P2, and P3) and one unidirectional (P4) promoter regions (Fig. 3 B, i). This cluster is conveniently organized such that successive activation of the three bidirectional promoter regions (P1, P2, and P3) is predicted to drive the expression of genes required to achieve the first, second, and third stages in indolotryptoline biosynthesis, respectively (Fig. 3C). |
回复此楼» 猜你喜欢
计算机、0854电子信息（085401-058412）调剂
已经有4人回复
-
基金申报
已经有3人回复
-
国自然申请面上模板最新2026版出了吗？
已经有9人回复
-
溴的反应液脱色
已经有6人回复
-
纳米粒子粒径的测量
已经有7人回复
-
常年博士招收(双一流，工科)
已经有4人回复
-
推荐一本书
已经有10人回复
-
参与限项
已经有5人回复
-
有没有人能给点建议
已经有5人回复
-
假如你的研究生提出不合理要求
已经有12人回复
2楼2016-03-28 00:35:06
3楼2016-03-28 21:44:30
|
en |
4楼2016-03-28 21:44:54
818james
铜虫 (著名写手)
- 翻译EPI: 140
- 应助: 59 (初中生)
- 金币: 7611.1
- 红花: 17
- 帖子: 1455
- 在线: 878.1小时
- 虫号: 3719023
- 注册: 2015-03-08
【答案】应助回帖
★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ...
bxzc123(fjtony163代发): 金币+30, 代发 2016-04-29 14:14:22
bxzc123(fjtony163代发): 金币+30, 代发 2016-04-29 14:14:30
bxzc123(fjtony163代发): 金币+30, 代发 2016-04-29 14:14:37
bxzc123(fjtony163代发): 金币+10, 代发 2016-04-29 14:14:44
fjtony163: 翻译EPI+1, 代发 2016-04-29 14:14:50
bxzc123(fjtony163代发): 金币+30, 代发 2016-04-29 14:14:22
bxzc123(fjtony163代发): 金币+30, 代发 2016-04-29 14:14:30
bxzc123(fjtony163代发): 金币+30, 代发 2016-04-29 14:14:37
bxzc123(fjtony163代发): 金币+10, 代发 2016-04-29 14:14:44
fjtony163: 翻译EPI+1, 代发 2016-04-29 14:14:50
|
The outer edges of the Lzr gene cluster were defined based on comparisons to the BE-54017 and cladoniamide gene clusters and a BLAST analysis of genes surrounding the core indolotryptoline biosynthesis genes (Fig. 3A). The biosynthesis of indolotryptolines is well-characterized, making it possible to predict the function of most genes in the Lzr gene cluster (32). The four key stages of indolotryptoline biosynthesis involve dimerization of oxo-tryptophan to form a chromopyrrolic acid, oxidative aryl–aryl coupling to form an indolocarbazole, “flipping” of one of the indole rings to form an indolotryptoline, and tailoring to generate the final product. The Lzr gene cluster is predicted to contain seven transcriptional units controlled by three bidirectional (P1, P2, and P3) and one unidirectional (P4) promoter regions (Fig. 3 B, i). This cluster is conveniently organized such that successive activation of the three bidirectional promoter regions (P1, P2, and P3) is predicted to drive the expression of genes required to achieve the first, second, and third stages in indolotryptoline biosynthesis, respectively (Fig. 3C). 通过与BE-54017 和 cladoniamide 基因簇比较以及对 indolotryptoline生物合成核心基因的外围基因进行比对分析(Fig. 3A)来确定 Lzr 基因簇的外部边界。Indolotryptolines的生物合成特点突出，根据这些特点可预测lzr基因簇中很多基因的功能。Indolotryptolines生物合成的四个主要的步骤包括氧络色氨酸的二聚化形成chromopyrrolic acid，氧化芳基连接成indolocarbazole，一个吲哚环翻转形成indolotryptoline，修饰形成最终产物。预测lzr基因簇含有七个转录单位，它们由三个双向(P1, P2, 和 P3)，一个单向(P4)的启动子区域控制(Fig. 3 B, i)。该基因簇的排列使人很易想到三个双向启动子区域(P1, P2, 和 P3)的相继启动是分别促使indolotryptoline生物合成的第一步，第二步，第三步反应所需的基因的表达。 |
5楼2016-04-01 11:58:26