24小时热门版块排行榜    

北京石油化工学院2026年研究生招生接收调剂公告
查看: 446  |  回复: 0

向阳华木

银虫 (初入文坛)

[求助] 求译Biosynthesis of Lycosantalonol a cis-Prenyl Derived Diterpenoid论文摘要

Terpenoid natural products are generally
derived from isoprenyl diphosphate precursors with trans
double-bond configuration, and no diterpenoid derived
from the cisoid precursor (Z,Z,Z)-nerylneryl diphosphate
(1) has yet been identified. Here further investigation of a
terpenoid biosynthetic gene cluster from tomato is
reported, which resulted in identification of a biosynthetic
pathway from 1, in a pathway featuring a number of
interesting transformations. Compound 1 is first cyclized
to a tricyclene core ring structure analogous to that found
in α-santalene, with the resulting diterpene termed here
lycosantalene (2). Quantum chemical calculations indicate
a role for the diphosphate anion coproduct in this
cyclization reaction. Subsequently, the internal cis double
bond of the neryl side chain in 2 is then further
transformed to an α-hydroxy ketone moiety via an epoxide
intermediate (3). Oxygen labeling studies indicate 3
undergoes oxidative conversion to lycosantalonol (4).
Thus, in addition to elucidating the cisoid origins of 4, this
work has further provided mechanistic insight into the
interesting transformations required for its production.

» 猜你喜欢

今天不只是昨天的延续,更是新的开始!
已阅   关注TA 给TA发消息 送TA红花 TA的回帖
相关版块跳转 我要订阅楼主 向阳华木 的主题更新
最具人气热帖推荐 [查看全部] 作者 回/看 最后发表
[考研] 085600,321分求调剂 +12 大馋小子 2026-04-04 13/650 2026-04-06 10:29 by dongzh2009
[考研] 308求调剂 +4 maverick^_^ 2026-04-03 4/200 2026-04-05 19:08 by 蓝云思雨
[考研] 307分材料专业求调剂 +7 Hll胡 2026-04-05 7/350 2026-04-05 18:47 by 无际的草原
[考研] 329求调剂 +17 miaodesi 2026-04-02 20/1000 2026-04-05 18:33 by 蓝云思雨
[考研] 070300化学求调剂 +17 小黄鸭宝 2026-03-30 17/850 2026-04-05 12:03 by 宁馨哈哈
[考研] 0854求调剂 +4 assdll 2026-04-04 4/200 2026-04-05 09:44 by zhq0425
[考研] 344材料与化工调剂 +9 调剂上岸玘 2026-04-03 9/450 2026-04-04 23:10 by happyddm
[考研] 341求调剂 +3 洛多罗 2026-04-02 4/200 2026-04-04 21:36 by 智能智慧
[考研] 277求调剂 +4 12A3 2026-04-02 5/250 2026-04-04 20:28 by 蓝云思雨
[考研] 278求调剂 +3 依旧! 2026-04-02 4/200 2026-04-04 20:27 by 蓝云思雨
[考研] 一志愿华北电力大学(北京),材料科学与工程学硕265,求调剂 +11 yelck 2026-04-03 12/600 2026-04-04 19:52 by dongzh2009
[考研] 342求调剂 +3 Liang7111 2026-04-04 5/250 2026-04-04 19:47 by dongzh2009
[考研] 321求调剂 +13 认真求上学 2026-04-02 13/650 2026-04-04 18:23 by macy2011
[考研] 求调剂 +9 akdhjs 2026-03-31 11/550 2026-04-03 13:32 by akdhjs
[考研] 土木水利328分求调剂 +6 疾风知劲草666 2026-04-02 6/300 2026-04-03 11:38 by znian
[考研] 抱歉 +5 田洪有 2026-03-30 5/250 2026-04-03 10:24 by linyelide
[考研] 材料340分调剂 +7 夏夜晚风_long 2026-04-02 9/450 2026-04-02 21:20 by dongzh2009
[考研] 一志愿北京科技大学085601材料工程英一数二初试总分335求调剂 +9 双马尾痞老板2 2026-04-01 9/450 2026-04-02 12:14 by oooqiao
[考研] 284求调剂 +12 小熊~~ 2026-03-31 12/600 2026-04-01 20:23 by 花??
[考研] 0703一志愿南师大334求调剂 +4 seven7yu 2026-03-30 4/200 2026-04-01 16:10 by oooqiao
信息提示
请填处理意见