赵欣磊,王建国,刘有才,周家玄,王北雨,李畅&张义君基于JAK2/STAT3信号通路探讨葛根素治疗绝经后骨质疏松症大鼠的作用机制包头医学院学报2025Issue1Pages25-31...

何智军通讯作者刘锋梁桂芳陈凯奇杜仲调节JAK2/STAT3信号通路对去卵巢骨质疏松大鼠的作用及机制研究中国中西医结合外科杂志2025年2期Pages223-22810.3969/j.issn.1007-6948.2025.02.012...

ShutingJia,YuyeJia,SufangLiang,LiqiangWuResearchprogressofmulti-targetHDACinhibitorsblockingtheBRD4-LIFR-JAK1-STAT3signalingpathwayinthetreatmentofcancerBioorganic&...

而是“如何做”：使用者想了解多肽与体内哪个受体结合（如GHRH受体、GHS受体），触发了怎样的下游信号通路（如JAK-STAT,MAPK），...3.预期效果与时间线：·现实的效果预期：不是“神奇逆龄”，...

Cai,KunYiAnti-LungCancerActivitiesof1,2,3-TriazoleCurcuminDerivativesviaRegulationoftheMAPK/NF-κB/STAT3SignalingPathwaysCHEMMEDCHEM2021Volume17;Issue3;202100676

ZhiboChang1,LingZhu1,JieYao1miR-210transferredbylungcancercell-derivedexosomesmayactasproangiogenicfactorincancer-associatedfibroblastsbymodulatingJAK2/STAT3pathwayClinSci(Lond...

615-5p的表观遗传调控及功能机制研究”（批准号81572790）“炎性因子激活NF-κB/STAT3通过表观遗传修饰调控肿瘤细胞恶性行为及前转移微环境形成的机制研究”（批准号91629302）“HPVE6/E7...

DaiX,YinC,ZhangY,etal.OstholeinhibitstriplenegativebreastcancercellsbysuppressingSTAT3JExpClinCancRes201837:1-11

WeinaMa12,YanhongLiu12,PanpanLei12,ManZhu12,XiaoyanPan1NovelCompound,ND-17,RegulatestheJAK/STAT,PI3K/AKT,andMAPKPathwaysandRestrainsHumanT-...22(5):404-413.doi:10.2174/...

YuhangShu,JingJingWang,MuhammadFarrukhNisar,ChunliWang*,GuangzhongWang*andKangXu*CoptischinensisFranchReliesonBerberinetoAlleviateStomachHeatSyndromethroughtheJAK2-STAT3-NF-...

下载这篇文献的SupplementalMaterial，不需要下载正文WanchunXu1,AmandaLaurenLee1,CindyLoKuenLam2,GoodarzDanaei3,...Real-WorldEvidenceFromaTargetTrialEmulationStudyAnnInternMed.2024...

sigma2issigmasquareinteger:i,j,nline,stat!...nlineif(abs(x-x0(i)).le.3*sigma)theny=y+y0(i)/(sigma*sqrt(2*pi))*exp(-1.0*(x-x0(i))*2.0&(2.0*sigma*sigma))endifenddowrite(outputfile,...

FuchengRen,aZitengLiang,...solid-statebatteriesEnergy&EnvironmentalScience2023EnergyEnviron.Sci.,2023,16,2579-2590https://pubs.rsc.org/en/content/articlelanding/2023/ee/d3ee00870c

YuYan1,Liu-BoZhang2,RuMa3,Man-NiWang2,JunHe1,Pei-PeiWang2,Qing-WenTao1,YuanXu4JolkinolideBamelioratesrheumatoidarthritisbyregulatingtheJAK2/STAT3signalingpathwayPhytomedicine...

③高通量药物筛选：将目标基因的启动子、调控元件（如NF-κB、STAT3等）或响应元件（如抗氧化反应元件ARE）与荧光素酶基因连接；④环境污染物检测：根据目标污染物选择对应元件（重金属污染...

转染或转导3.筛选与验证4.单克隆筛选5.基因敲除验证基因敲除细胞应用敲除细胞作为重要...敲除JAK1后，STAT磷酸化水平可通过Westernblot检测是否发生变化，从而确定其在信号转导过程中的作用。...

等药化权威期刊发表多篇论文，主持国自然青年基金等科研项目，参与研发的STAT3双功能磷酸化抑制剂已获中美双临床I期批件。【招聘岗位】2026年博士研究生【招生要求】硕士学历，药物化学/...

等药化权威期刊发表多篇论文，主持国自然青年基金等科研项目，参与研发的STAT3双功能磷酸化抑制剂已获中美双临床I期批件。【招聘岗位】科研助理1-2名【岗位要求】硕士学历，药物化学/有机...

发现APLNR通过调节靶细胞中的JAK-STAT信号传导来调节T细胞抗肿瘤反应的新作用，APLNR的缺失抑制JAK-STAT通路，从而削弱IFN-γ...案例3靶细胞：胰腺细胞系HupT3和KP4_MSLN效应细胞：MSLNCAR-T...

DeliveringCpGandSTAT3siRNAtoEffectivelyInduceWhole-BodyAntitumorImmuneResponseAdv.Mater.2021n/ahttps:/advanced.onlinelibrary.wiley.com/doi/10.1002/adma.202100628求pdf全文

JingruLiao1,WenjunZhao1,YuweiZhang1,ZebinZou1,QilinZhang1,DongqiuChen2,BingDu1,PanLi3...κB/STAT3signalingpathwaysJEthnopharmacol2024Dec5335:118677.10.1016/j.jep.2024.118677

TangnuerYushanjiang&FengGaoResatorvid(TAK-242)AmelioratesUlcerativeColitisbyModulatingMacrophagePolarizationandTHelperCellBalanceviaTLR4/JAK2/STAT3SignalingPathwayInflammation...

Jing-RuiZhou,YiLiao,Le-QingCao,RuiMa,YunHe,NaLi,Dan-PingZhu,Xiao-SuZhao,Xiao-JunHuang,Yu-...6/sIL-6R/JAK1/STAT3PathwayTheJournalofInfectiousDiseases2025Jan202025Jan20...

HyoInKim，etalQuercetinInducesApoptosisinGlioblastomaCellsbySuppressingAxl/IL-6/STAT3SignalingPathwayAmJChinMed202149(3):767-78410.1142/S0192415X21500361

galn/lpsinducedacuteliverfailurethroughrepolarizingm1macrophagetom2-likephenotypeviaactivationoftheil-10/jak2/stat3signalingpathway”的研究论文。该研究主要针对肝实质细胞无法...