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分类 共搜索到 86 个相关话题(最多显示前5000个) 作者 最后发表
文献求助 Discovery of aminopiperidine-based Smac mimetics as IAP ...
Hennessy,EdwardJ.;etalDiscoveryofaminopiperidine-basedSmacmimeticsasIAPantagonistsBioorganic&MedicinalChemistryLetters201222(4),1690-1694.
 林雨暮 2023-01-10 01:05
绿色求助(高悬赏) 文献求助
NicolásMacíasImportanceofBodyWaterintheEfficacyofConvectiveSoluteTransportinOnlineHemodiafiltrationTheraeuticapheresisanddialysis2017Volume21,?Issue1Pages?88-95...
 baike001ok 2022-11-16 01:54
文献求助 Discovery of aminopiperidine-based Smac mimetics as IAP ...
Bioorganic&MedicinalChemistryLetters(2012),22(4),1690-1694.Hennessy,EdwardJ.;etalDiscoveryofaminopiperidine-basedSmacmimeticsasIAPantagonistsBioorganic&...
 林雨暮 2022-10-12 12:03
论文投稿 请大神帮忙看下这篇论文现在是不是已经被EI收录了啊？...
XianzhongZhuPublishedin:2021FifthInternationalConferenceonI-SMAC(IoTinSocial,Mobile,AnalyticsandCloud)(I-SMAC)DateofConference:11-13November2021DateAddedtoIEEEXplore:20December...
 willbuilder 2022-08-07 02:05
生物科学 凋亡明星靶点——Bcl-2家族蛋白抑制剂
smac/diablo抑制iaps激活caspase9。caspase9激活caspase3，这是caspase激活级联的起始步骤。外源性途径可被fas、tnf等细胞表面受体激活，进而激活caspase8，导致caspase3活化和细胞破坏。...
 absinbio 2020-11-12 07:49
文献求助 Effect of Khat on apoptosis and related gene Smac/DIABLO ...
www.ncbi.nlm.nih.gov/pubmed/?term=Effect+of+Khat+on+apoptosis+and+related+gene+Smac%2FDIABLO+expression+in+the+cerebral+cortex+of+rats+following+transient+focal+ischemia
 tanjuan135 2019-05-21 01:44
仿真模拟 SMAC
有偿求一位熟悉用matlab仿真smac协议的大神，感谢各位大神
 欣宝宝哒 2018-09-24 10:03
文献求助 求助全文 Smac mimetics and innate immune stimuli synergize ...
JohnCBell&RobertGKornelukinfo'.1.'][info2]Smacmimeticsandinnateimmunestimulisynergizetopromotetumordeathinfo'.2.'][info3]NatureBiotechnologyinfo'.3.'][info...
 八月FXR 2017-12-08 10:55
文献求助 Cationic liposome co-encapsulation of SMAC mimetic and zVAD ...
[info2]Cationicliposomeco-encapsulationofSMACmimeticandzVADusinganovellipidbilayerfusionloadedwithMLKL-pDNAfortumourinhibitioninvivo.info'.2.'][info3]...
 小米粒儿琳 2017-09-14 11:35
文献求助完结子版 dependent mitochondrial amplification step ...Smac mimetic/glu
amplificationstepcontributestoSmacmimetic/glucocorticoid-inducednecroptosis.info'.2.'][info3]CellDeathDiffer.2017Jan;24(1):83-97.doi:10.1038/cdd.2016.102.info'.3....
 长春竹 2017-03-31 01:15
文献求助完结子版 Therapeutic targeting of necroptosis by Smac mimetic ...
targetingofnecroptosisbySmacmimeticbypassesapoptosisresistanceinacutemyeloidleukemiacells.info'.2.'][info3]Oncogeneinfo'.3.'][info4]2017info'.4.'][info5]36...
 长春竹 2017-03-31 01:32
文献求助 The IAP Protein Family,SMAC Mimetics and Cancer Treatment
[info1]KohMiurainfo'.1.'][info2]TheIAPProteinFamily,SMACMimeticsandCancerTreatmentinfo'.2.'][info3]CriticalReviews?inOncogenesisinfo'.3.'][info4]2016info'.4...
 陈红分 2017-02-28 05:12
文献求助 求助 cancer letter 一篇
[info2]AnovelSmacmimeticAPG-1387demonstratespotentantitumoractivityinnasopharyngealcarcinomacellsbyinducingapoptosisinfo'.2.'][info3]cancerletterinfo'.3.']...
 titanheart 2017-01-16 01:12
文献求助 文献求助
synthesisandbiochemicaltestingofnovelandpotentSmacpeptido-mimeticsinfo'.2.'][info3]Bioorganic&MedicinalChemistryLettersinfo'.3.'][info4]2005info'.4.'][info5]...
 lvgang89 2017-01-11 05:49
文献求助 在线等，求一篇文献，有链接和Doi
RadiobiologyKyiv,Ukraineinfo'.1.'][info2]TheIAPProteinFamily,SMACMimeticsandCancerTreatmentinfo'.2.'][info3]CriticalReviews?inOncogenesisinfo'.3.'][info4]2016...
 chem_liu 2016-12-27 06:10
资源求助 求助一份Smac类似物LCL161的大鼠药代动力学数据的文献，谢谢！
如题，求助一份Smac类似物LCL161的大鼠药代动力学数据的文献，谢谢！
 zdm2011225 2016-09-21 06:54
生物科学 细胞凋亡检测之选择指南
这包括凋亡抑制剂（IAP）家族和SMAC（IAP的抑制剂），它们的小分子模拟物已被开发出，以促进癌症中的细胞凋亡。了解凋亡，有许多方式，从通用的（它是否发生？到特异的（针对caspase9和Bax...
 xmczhby 2016-08-05 08:45
文献求助 求文献一篇
D.P.info'.1.'][info2]Design,synthesisandevaluationofmonovalentSmacmimeticsthatbindtotheBIR2domainoftheanti-apoptoticproteinXIAPinfo'.2.'][info3]Bioorganic...
 huge2007 2016-07-30 07:41
药学 细胞凋亡机制的发现
在研究中，王偶然发现GST融合表达的Smac完全没有活性，这提示Smac的N端是极其重要的。SmacN端的四个氨基酸与它在果蝇中的同源蛋白非常保守。进一步分析发现，体外合成的这四个氨基酸就有...
 natmed 2016-07-24 06:06
文献求助 Science Translational Medicine 文献求助
SMACmimeticbirinapanttoinducenecroptosisandtreatacutemyeloidleukemiainfo'.2.'][info3]ScienceTranslationalMedicine18May2016:Vol.8,Issue339,pp.339ra69info'.3...
 lzuhgt 2016-07-21 08:37
文献求助 RGD/SMAC mimetic conjug
evaluationofdualactioncyclo-RGD/SMACmimeticconjugatestargetinga(v)beta(3)/a(v)beta(5)integrinsandIAPproteinsinfo'.2.'][info3]ORGANIC&BIOMOLECULARCHEMISTRYinfo'...
 清晨的枫叶 2016-06-12 01:23
文献求助 The caspase-8 inhibitor emricasan combines with the SMAC ...
inhibitoremricasancombineswiththeSMACmimeticbirinapanttoinducenecroptosisandtreatacutemyeloidleukemiainfo'.2.'][info3]SciTranslMedinfo'.3.'][info4]2016...
 长春竹 2016-06-11 03:36
文献求助 Clinical Cancer Research文献求助
[info1]SimoneFuldainfo'.1.'][info2]PromisesandChallengesofSmacMimeticsasCancerTherapeuticsinfo'.2.'][info3]ClinicalCancerResearchinfo'.3.'][info4]2015info'.4...
 jerryyn 2016-02-17 03:07
文献求助 求助文献一篇
Whitstoninfo'.1.'][info2]DiscoveryofaNovelClassofDimericSmacMimeticsasPotentIAPAntagonistsResultinginaClinicalCandidatefortheTreatmentofCancer(AZD5582...
 liuyun0126 2015-12-30 08:25
文献求助 求文献
Fesik1info'.1.'][info2]StructuralbasisforbindingofSmac/DIABLOtotheXIAPBIR3domaininfo'.2.'][info3]natureinfo'.3.'][info4]21December2000info'.4.'][info5]408,...
 annfk0316 2015-11-30 01:22
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