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分享——遗传药理学的临床应用 （英文版）
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"Clinical Applications of Pharmacogenetics" ed. by Despina Sanoudou ITAe | 2012 | ISBN: 9789535103899 | 302 pages | PDF | 8 MB This book presents Pharmacogenetic examples from a broad spectrum of different drugs, for different diseases, which are representative of different stages of evaluation or application. It has been designed so as to serve both the unfamiliar reader through explanations of basic Pharmacogenetic concepts, the clinician with presentation of the latest developments and international guidelines, and the research scientist with examples of Pharmacogenetic applications, discussions on the limitations and an outlook on the new scientific trends in this field. The rapidly evolving field of Pharmacogenetics aims at identifying the genetic factors implicated in the inter-individual variation of drug response. These factors could enable patient sub-classification based on their treatment needs thus expediting drug development and promoting personalized, safer and more effective treatments. Contents Preface Part 1 Pharmacogenetics - Theory and Practice 1 Pharmacogenetics: Matching the Right Foundation at Personalized Medicine in the Right Genomic Era 2 Multiplexed Pharmacogenetic Assays for SNP Genotyping: Tools and Techniques for Individualizing Patient Therapy Part 2 Pharmacogenetics in Oncology 3 Role of Pharmacogenetics in Gastrointestinal Cancer 4 Pharmacogenomics of Thiopurine S-Methyltransferase: Clinical Applicability of Genetic Variants 5 S-Adenosy I methionine: A Novel Factor in the Individualization of Thiopurine Therapy Part 3 Pharmacogenetics in Cardiovascular Disease 6 Current Status of Pharmacogenetics in Antithrombotic Drug Therapy 7 Clinical Implications of Genetic Admixture in Hispanic Puerto Ricans: Impact on the Pharmacogenetics ofCYP2C19 and PON1 Part 4 Emerging Role of Pharmacogenetics in Other Disciplines 8 Neuropharmacogenetics of Major Depression: Has the Time Come to Take both Sexes into Account? 9 Pharmacogenetics of Asthma 10 Pharmacogenomics in Gastroenterology 11 The Pharmacogenetics of the Anti malaria I Amodiaquine 12 Pharmacogenetics and Obstetric Anesthesia and Analgesia Part 5 Future Prospects 13 Beyond Pharmacogenetics  ITAe | 2012 | ISBN: 9789535103899 | 302 pages | PDF | 8 MB |
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2016-02-19 10:22:10, 7.74 M
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