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2016年新著——下一代测序（英文版）
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"Next Generation Sequencing: Advances, Applications and Challenges" ed. by Jerzy K Kulski InTAvE | 2016 | ISBN: 9535122401 9789535122401 | 449 pages | PDF | 23 MB This book written by experts covers various aspects of Next generation sequencing (NGS) including genomics, transcriptomics and methylomics, the sequencing platforms, and the bioinformatics challenges in processing and analysing huge amounts of sequencing data. The book is of value to all who are interested in DNA sequencing and bioinformatics across all fields of the life sciences. Next generation sequencing (NGS) has surpassed the traditional Sanger sequencing method to become the main choice for large-scale, genome-wide sequencing studies with ultra-high-throughput production and a huge reduction in costs. The NGS technologies have had enormous impact on the studies of structural and functional genomics in all the life sciences. Following an overview of the evolution of NGS in the brave new world of omics, the book examines the advances and challenges of NGS applications in basic and applied research on microorganisms, agricultural plants and humans. Contents Preface 1 Next-Generation Sequencing — An Overview of the History, Tools, and “Omic” Applications 2 Next Generation Sequencing in Aquatic Models 3 MHC Genotyping in Human and Nonhuman Species by PCRbased Next-Generation Sequencing 4 Transcriptomic Profiling Using Next Generation Sequencing - Advances, Advantages, and Challenges 5 Computational Analysis and Integration of MeDIP-seq Methylome Data 6 Analysis of Next-generation Sequencing Data in Virology - Opportunities and Challenges 7 RNA-seq – Revealing Biological Insights in Bacteria 8 Dealing with the Data Deluge – New Strategies in Prokaryotic Genome Analysis 9 Reaping the Benefits of Next-generation Sequencing Technologies for Crop Improvement — Solanaceae 10 Perspectives on the Application of Next-generation Sequencing to the Improvement of Africa’s Staple Food Crops 11 Hop-variety Identification Using First- and Second-generation Sequencing 12 Analysis of Haplotype Sequences 13 On Genotyping Polymorphic HLA Genes — Ambiguities and Quality Measures Using NGS 14 DNA-based Diagnosis of Uncharacterized Inherited Macrothrombocytopenias Using Next-generation Sequencing Technology with a Candidate Gene Array 15 Clinical Implementation of Next-generation Sequencing in the Field of Prenatal Diagnostics 16 Impact of Gene Annotation on RNA-seq Data Analysis  InTAvE | 2016 | ISBN: 9535122401 9789535122401 | 449 pages | PDF | 23 MB |
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2016-01-18 15:54:36, 23.48 M
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