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清华大学，汕头多学科研究中心－－陈国强
★ ★ ★ ★ ★ ★ ★ ★
zhangwj(金币+6,VIP+0):谢谢分享！
zhangwj(金币+2,VIP+0):悬赏金！
Group Name:
清华大学微生物实验室，汕头大学多学科研究中心（李嘉诚基金会）
Group Leader:
陈国强
Affiliation:
清华大学，汕头大学
Research Interest:
主要从事PHAs可降解生物材料的开发，积极参与绿色材料的推广，包括08北京奥运一次性可降解塑料的检测工作。
主要研究领域是微生物作为一个合成体系的应用，包括：
1． 微生物合成新型高分子-聚羟基脂肪酸酯及其作为组织工程材料的应用：
2． 分子进化技术和代谢工程技术在微生物菌种改良中的应用
3． 微生物生产新型材料和新型化合物的发酵工程技术开发
4． 微生物合成新型手性化合物的代谢工程研究
Research Highlight:
http://microbes.biosci.tsinghua.edu.cn:8002/ch.htm
http://mrc.stu.edu.cn/Chinese/Intro/Intro.htm
在国际学术期刊上共发表有关生物材料PHA的论文120多篇，被引用一千三百多次。获得授权专利19项，20多个公开专利申请。现担任国际学术期刊《Applied Microbiology and Biotechnology》、《Biomaterials》、《Artificial Cells, Blood Substitutes and Biotechnology》和《Asia Pacific Biotech News》编委，同时担任国内核心学术期刊《生物工程学报》副主编以及《生物加工过程》、《高分子学报》和《生物技术产业》编委。担任联合国工业发展暑— 国际高科技中心(ICS-UNIDO)的应用化学专家组生物可降解材料委员和中国生物工程学会常务理事。陈教授多次组织了有关生物新材料PHA的国际学术会议，并在国际相关学术会议上应邀做了多次大会和特邀报告。主持了多项国家生物塑料PHA重大的基础研究和产业化项目。在过去的五年里，陈教授获得的荣誉包括：教育部长江学者特聘教授、第八届中国青年科技奖、自然科学基金委国家杰出青年、纽伦堡国际发明奖、国家发明二等奖(排名第一)，茅以升科技奖、教育部高校青年教师奖等。曾连续6年获得清华大学学生“良师益友”的光荣称号。
International Publication
1 Chen GQ, Koenig KH and Lafferty RM.Production of poly-D(-)-3-hydroxybutyrate and poly-D(-)-3-hydroxyvalerate by strains of Alcaligenes latus . Antonie van Leewenhoek 60 (1991) 61-66
2 Chen GQ , Koenig KH and Lafferty RM. Occurrence of poly-D (-)-3-hydroxyalkanoaies in the genus Bacillus . FEMS Microbiol. Letters 84 (1991) 173-176
3 Haigermoser C, Chen GQ , Grohman.E, Hrabak O and Schwab H. Stability of r-microbes: Stabilization of plasmid vectors by the partitioning function of broad-host- range plasmid RP4. J. Biotech 28 (1993) 219-299
4 Chen GQ , .Wu L, Coombes A, Davis SS and Illum L Preparation of human serum albumin microspheres by a novel acetone-heat denaturation method. J. Microencapsulation 11(1994) 395-407
5 Chen GQ and Page WJ The effect of substrate on the molecular weight of poly-beta-hydroxybutyrate produced by Azotobacter vinelandii UWD. Biotechnol. Lett 16 (1994) 155-160
6 Chen GQ and Page WJ. Production of poly-beta-hydroxybutyrate by Azotobacter vinelandii UWD in a two-stage fermentation process. Biotechnol. Techniques 11(1997) 347-350
7 Yu PH, Chua H, Huang AL. Lo W and Chen GQ . Conversion of Food industrial Wastes into Bio-plastics. Appl. Biochem. and Biotechnol. 70 (1998) 603-614
8 Kim TN, Feng QL, Kim JO,. Wu J, Wang H, Chen GC and Cui FZ. Anti-microbial effects of metal ions (Ag + , Cu 2+ , Zn 2+ ) in hydroxyapatite. J. Materials Science: Materials in Medicine 9 (1998) 129-134
9 He WN, Tian WD, Zhang G, Chen GQ and Zhang ZM. Production of novel polyhydroxyalkanoates by Pseudomonas stutzeri 1317 from glucose and soybean oil. FEMS Microbiol. Lett. 169 (1998) 45-49
10 Hong K, Sun SQ, Tian WD, Chen GQ, Huang W. A rapid method for detecting bacterial PHA in intact cells by FT-IR. Appl. Microbiol. Biotechnol. 51 (1999) 523-526
11 Yao J, Zhang G, Wu Q, Chen GQ and Zhang RQ. Production of polyhydroxyalkanoates by Pseudomonas nitroreducens . Antonie van Leewenhoek 75 (1999) 345-349
12 He WN, Zhang ZM, Hu P and Chen GQ . Microbial synthesis and characterization of polyhydroxyalkanoates by strain DG17 from glucose. Acta Polymerica Sinica 6 (1999) 709-714
13 Zhang DM, Cui FZ, Luo ZS, Lin YB, Zhao K and Chen GQ . Wettability improvement of bacterial polyhydroxyalkanoates via ion implantation.. Surface & Coating Technology 131 (2000) 1-5
14 Cui FZ, Sun SQ, Zhang DM , Ma ZL, Chen GQ . Molecular alteration and carbonization of aspartic acid upon N+ ion irradiation. NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS 169 (2000) 48-53
15 Zhang DM , Cui FZ, Sun SQ, Lin YB, Tian MB, Chen GQ . Influence of low-energy ion irradiation on plasma membrane permeability of cells. CHINESE PHYSICS LETTERS 17 (2000) 61-63
16 Xi JZ, Wu Q, Yan YB, Zhang ZM, Yu HP, MK Cheung, Zhang RQ and Chen GQ . Hyperproduction of polyesters consisting of medium-chain-length hydroxyalkanoate monomers by strain Pseudomonas stutzeri 1317. Antonie van Leeuwenhoek 78 (2000): 43-49
17 Hong K, Chen GQ , PH Yu, Zhang G and Liu Y. Effect of C/N ratio on monomer composition of polyhydroxyalkanoate (PHA) produced by Pseudomonas mendocina 0806 and Pseudomonas pseudoalkaligenus YS1, Appl. Biochem. and Biotechnol. 84-86 (2000): 971-980
18 Feng QL, Wu J, Chen GQ , Cui FZ, Kim TN, Kim JO. A mechanistic study of the antibacterial effect of silver ions on Escherichia coli and Staphylococcus aureus . J Biomed Mater Res 52 (4) (2000) 662-8
19 Sun SQ, Zhou Q, Hou WJ, Wu Q, Chen GQ . Study on mechanism of different PHAs during heating by FTIR. Spectroscopy and Spectral Analysis 20 (5) (2000) 677-678
20 Tian WD, Hong K, Chen GQ , Wu Q, Zhang RQ and Huang WY . Production of polyesters consisting of medium chain length 3-hydroalkanoic acids by Pseudomonas mendocina 0806 from various carbon sources. Antonie van Leewenhoek 77 (2000) 31-36
21 Chen GQ , Wu Q, Zhao K, Yu HP & Chan A. Chiral Biopolyesters- Polyhydroxyalkanoates Synthesized by Microorganisms. Chinese J of Polymer Science 18 (2000) 389-396
22 Chen GQ, Wu Q, Xi JZ, Yu HP and Chan A. Microbial production of biopolyesters-polyhydroxyalkanoates. Progress of Natural Sciences 10 (2000) 843-850
23 Wu Q, Sun SQ, Yu PHF, Chen AXZ, Chen GQ . Environmental Dependence of Microbial Synthesis of Polyhydroxyalkanoates. Acta Polymerica Sinica 6 (2000) 751-756
24 Chen GQ, Xu J, Wu Q, Zhang ZM and Ho KP. Synthesis of copolyesters consisting of medium-chain-length-hydroxyalkanoates by Pseudomonas stutzeri 1317. Reactive & Functional Polymers 48 (2001) 107-112
25 Tian G, Wu Q, Sun SQ, Noda I, Chen GQ . Study of Thermal Melting Behavior of Microbial Polyhydroxyalkanoates Using Two-Dimensional Fourier-Transform Infrared FT-IR Correlation Spectroscopy. Appl. Spectroscopy 55(7) (2001) 888-894
26 Wu Q, Tian G, Wu Q, Sun SQ, Noda I, Chen GQ Study of Microbial Poly(hydroxybutyrate-co-hydroxyhexanoate) Using Two-Dimensional Fourier-Transform Infrared Correlation Spectroscopy. J Appl Polym Sci. 82 934-940 (2001)
Bookchapters
1. Foundations and Applications of Industrial Microbiology (By XU H and CHEN GQ et al.) Chinese Academic Publisher (1991)
2. Microbial Synthesis in Polymer Sciences Across the Century (ed. Hu HJ et al) Chen GQ. Chemical Engineering Publisher (2001)
3. Production and Application of Microbial Polyhydroxyalkanoates. in “Biodegradable Polymers and Plastics” (Ed. Chiellini E and Solaro R). Wkap Publisher (2003) pp155-166
4. Biopolymers (Translated By Chen GQ et al) (Chemical Industry Publisher) (2004)
5. Polyhydroxyalkanoates in Biodegradable Polymers in “Biodegradable Polymers for Industrial Applications” (Ed. Smith Ray) (Woodhead Publishing Ltd. Co.) (2005)
6. Natural Biomass Engineering Materials 天然生物质工程材料 in 《中国新材料产业发展报告 2005 》 .( China Material Research Society). (Submitted in 2005)
7. Frontier and Progress of Polymer Research 《高分子科学前沿与进展》 (Ed. DONG Jianhua) (Natural Science Foundation of China) (Submitted in 2005)
Issued Patents
1. Chen GQ . Li MQ, Chen JC. Zhao K and Wu Q. A method for separation of intracellular polyhydroxyalkanoates. 一种分离细胞内聚羟基脂肪酸酯的方法 . Chinese Patent ZL 98 1 00266.8 (2001)
2. Zhou Q, Gu YS and Chen GQ A new process for high efficient fermentative production of alcohol by yeast cultivated in molasses. 一个用废糖蜜为原料高效发酵生产酒精的新技术 . Chinese Patent No. ZL 99121907.4 (2002)
3. Chen GQ , Yang XS, Zhao K, Chen JC. The application of poly(3-hydroxybutyrate-co- hydroxyhexanoate) as tissue engineering materials. 一种生物材料和为组织工程材料 . Chinese Patent No. ZL 01 1 29618.6 (2004)
4. Chen GQ , XI JZ ， WU Q, Chen JC. Production of Chiral 3- (R)-Hydroxybutyric Acid Using Recombinant Escherichia coli. 采 用重组大肠杆菌生产手性 3-(R) －羟基丁酸的方法 . Chinese Patent Application no. ZL 01118668.2 (2004)
5. Chen GQ , ZHANG J, WU Q, CHEN JC An Aeromonas hydrophila Strain and Its Application. 一株嗜水气单胞菌及其应用 . Chinese Patent No. ZL 01134576.4 (2004)
6. Chen GQ, GAN ZX. A Method for Extraction and Purification of Intracellular Microbial Polyhydroxyalkanoates. 一种从细菌体内分离提取聚羟基脂肪酸酯的方法 . Chinese Patent No. ZL 02130725.3 (2005)
7. Chen GQ , GAO HJ, WU Q, CHEN JC A Method for Production of D-(-)3-hydroxybutyric acid. 一种生产 D-(-)- 3 － 羟基丁酸的方法 . Chinese Patent No. ZL 02100014.X (2005)
8. Chen GQ , ZHENG Z and WU Q A Method for Production of 3-Hydroxydecanoate. 一种生产 3 －羟基癸酸的方法 . Chinese Patent No. ZL 02117571.3 (2005) |
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