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tjuhaoran

铜虫 (小有名气)

应助: 2 (幼儿园)
金币: 175.2
散金: 1693
红花: 181
帖子: 215
在线: 73.3小时
虫号: 3136846
注册: 2014-04-14
专业: 生物大分子结构与功能

[交流] 博士后职位信息，伦敦癌症研究院，生物信息学，基因组进化研究！已有2人参与

单位
The Institute of Cancer Research, ICR, Translational Oncogenomics Lab, Division of Molecular Pathology

项目简介
The Gerlinger group investigates the evolutionary dynamics of solid tumours during progression and drug therapy.

Key aims are to reveal recurrent evolutionary trajectories during cancer drug treatment, how therapy influences genomic instability mechanisms and how cancer immunogenicity impacts on drug resistance evolution. This work should define genotypes towards which cancer cell populations converge during therapy and the mechanisms driving cancer genomic plasticity. Our ultimate goal is to target these therapeutically in order to improve the survival of cancer patients.

The successful candidate will analyse the genome evolution of longitudinally collected colorectal and gastro-oesophageal cancer specimens. Whole genome, exome, single cell and RNA-Seq data is being generated in the sequencing facility of the ICR Centre for Evolution and Cancer which is funded by a Wellcome Trust Strategic Award. The laboratory is also closely involved in the colorectal cancer Genomics England Clinical Interpretation Partnership which will provide opportunities to analyse colorectal cancer specimens sequenced as part of the Genomics England 100.000 Genome Project.

We are looking for an outstanding and enthusiastic bioinformatician/computational biologist who recently completed a PhD or already has some experience at postdoctoral level. The candidate should have a strong interest in cancer genomics and evolution and ideally experience in cancer next-generation sequencing data analysis, copy number and structural variant analysis. He or she will work closely with our team of postdocs, bioinformaticians, wet lab and computational PhD students to further develop sequencing and bioinformatics techniques.

截止日期
20151112

联系人
Dr Gerlinge (marco.gerlinger@icr.ac.uk)

详细信息
http://mp.weixin.qq.com/s?__biz= ... e=4#wechat_redirect

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