| 查看: 90 | 回复: 0 | |||
| 当前主题已经存档。 | |||
lcl6932木虫 (著名写手)
|
[交流]
DNA Methylation Microarrays: Experimental Design and Statistical Analysis
|
||
|
DNA Methylation Microarrays: Experimental Design and Statistical Analysis (Chapman & Hall/Crc Biostatistics Series) By Sun-Chong Wang, Art Petronis Publisher: Chapman & Hall/CRC Number Of Pages: 256 Publication Date: 2008-04-24 ISBN-10 / ASIN: 1420067273 ISBN-13 / EAN: 9781420067279 Binding: Hardcover Providing an interface between dry-bench bioinformaticians and wet-lab biologists, DNA Methylation Microarrays: Experimental Design and Statistical Analysis presents the statistical methods and tools to analyze high-throughput epigenomic data, in particular, DNA methylation microarray data. Since these microarrays share the same underlying principles as gene expression microarrays, many of the analyses in the text also apply to microarray-based gene expression and histone modification (ChIP-on-chip) studies. After introducing basic statistics, the book describes wet-bench technologies that produce the data for analysis and explains how to preprocess the data to remove systematic artifacts resulting from measurement imperfections. It then explores differential methylation and genomic tiling arrays. Focusing on exploratory data analysis, the next several chapters show how cluster and network analyses can link the functions and roles of unannotated DNA elements with known ones. The book concludes by surveying the open source software (R and Bioconductor), public databases, and other online resources available for microarray research. Requiring only limited knowledge of statistics and programming, this book helps readers gain a solid understanding of the methodological foundations of DNA microarray analysis. http://www.filefactory.com/file/e0e104/n/1420067273_rar |
回复此楼» 猜你喜欢
拟解决的关键科学问题还要不要写
已经有8人回复
-
最失望的一年
已经有11人回复
-
求推荐英文EI期刊
已经有5人回复
-
存款400万可以在学校里躺平吗
已经有27人回复
-
请教限项目规定
已经有4人回复
-
国自然申请面上模板最新2026版出了吗？
已经有20人回复
-
26申博
已经有3人回复
-
基金委咋了？2026年的指南还没有出来？
已经有10人回复
-
基金申报
已经有6人回复
-
疑惑？
已经有5人回复