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sundy93

金虫 (小有名气)

[求助] 求翻译2句话

1  In the recent past, in our laboratory, ascorbyl palmitate
(ASP) vesicles (aspasomes) were prepared and studied for
permeation-enhancing properties (Gopinath et al., 2004)
and their utility as a carrier for drug targeting to brain
in mice was also demonstrated (unpublished data).
2  However, no attempt has been made to address the utility of antioxidant
in targeting tumor tissue. The prevalence of leaky vascular
endothelium at the tumor tissue allows the extravasation of
the long-circulating liposomes loaded with an antiox

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武汉一心一译

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sundy93: 金币+3, ★★★★★最佳答案 2015-09-18 18:08:01
1  In the recent past, in our laboratory, ascorbyl palmitate (ASP) vesicles (aspasomes) were prepared and studied for permeation-enhancing properties (Gopinath et al., 2004) and their utility as a carrier for drug targeting to brain in mice was also demonstrated (unpublished data).
1近期,我实验室成功制备了抗坏血酸棕榈酸酯囊泡,并研究了其加强型渗透性能。(Gopinath等人2004年的研究),同时根据未发表研究证实,该抗坏血酸棕榈酸酯囊泡可作为载体,靶向给药至实验鼠大脑。

2  However, no attempt has been made to address the utility of antioxidant
in targeting tumor tissue. The prevalence of leaky vascular endothelium at the tumor tissue allows the extravasation of the long-circulating liposomes loaded with an antiox
然而, 目前还没有任何实验证明(该物质的),在定向给药肿瘤组织时的抗氧化剂功效。肿瘤组织中,血管内皮发生破漏,使得带有抗氧化功能的长循环脂质体溢出。
2楼2015-09-18 10:57:57
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Frieda2014

新虫 (初入文坛)

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sundy93: 金币+2, ★★★很有帮助 2015-09-18 18:08:34
引用回帖:
2楼: Originally posted by 武汉一心一译 at 2015-09-18 10:57:57
1  In the recent past, in our laboratory, ascorbyl palmitate (ASP) vesicles (aspasomes) were prepared and studied for permeation-enhancing properties (Gopinath et al., 2004) and their utility as a ca ...

有两个地方想补充说明一下,按照药理角度。加强型渗透性能直接译为增强渗透即可。
肿瘤组织中,血管内皮相对于正常血管来说排列疏松,使得这个脂质体能能够透过血管达到肿瘤组织,也就是EPR效应。
3楼2015-09-18 15:18:10
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sundy93

金虫 (小有名气)

引用回帖:
2楼: Originally posted by 武汉一心一译 at 2015-09-18 10:57:57
1  In the recent past, in our laboratory, ascorbyl palmitate (ASP) vesicles (aspasomes) were prepared and studied for permeation-enhancing properties (Gopinath et al., 2004) and their utility as a ca ...

谢谢哟

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4楼2015-09-18 18:08:21
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sundy93

金虫 (小有名气)

引用回帖:
3楼: Originally posted by Frieda2014 at 2015-09-18 15:18:10
有两个地方想补充说明一下,按照药理角度。加强型渗透性能直接译为增强渗透即可。
肿瘤组织中,血管内皮相对于正常血管来说排列疏松,使得这个脂质体能能够透过血管达到肿瘤组织,也就是EPR效应。...

谢谢

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5楼2015-09-18 18:08:44
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