| 查看: 826 | 回复: 1 | ||||
[交流]
探寻老年痴呆症的秘密，伦敦国王学院博后研究 已有1人参与
|
|
单位：Institute of Psychiatry, Psychology and Neuroscience, King’s College London 项目简介: The post holder will be a member of the blood-based biomarker group working on discovery and characterisation of a plasma-based biomarker for Alzheimer’s disease. The biomarker group has performed numerous discovery-based proteomic studies with different study designs such as caseversus control, progression and pathology markers and have identified a number of key protein targets. The biomarker group has access to well-characterised sample cohorts to enable further development of discovery projects. The aim of the project will be to investigate a novel biological marker of Alzheimer’s disease. We have recently identified a plasma protein that has been implicated in both the brain’s response to stress, and a pathway known to play a role in b-amyloid aggregation – the wnt-planar cell polarity pathway. We intend to replicate our initial results in plasma samples from different clinical and non-clinical populations to examine whether levels of this protein differ by disease state, and whether this protein is associated with other biological and psychological indicators of Alzheimer’s disease. We will additionally investigate the comparability of peripheral protein levels with markers in central nervous system, and will examine whether a novel intervention alters its expression. The role will also involve participation in other ongoing studies of the group. The project will be jointly supervised by Dr Natalie Marchant, Dr Richard Killick and Dr Abdul Hye at the Institute of Psychiatry, Psychology and Neuroscience. Dr Hye will provide primary supervision. Applicants must be highly motivated to carry out basic research and hold a relevant undergraduate degree (Biology/Neuroscience or equivalent) with a good background in protein biochemistry. Applicants should be able to work independently, be able to interact well with other team members and have effective communication skills for both supervisory and dissemination purposes. 截止日期: 2015.10.10 薪水：?27,057 per annum 联系人: Dr Abdul Hye（abdul.1.hye@kcl.ac.uk） 详细信息: http://mp.weixin.qq.com/s?__biz= ... e=4#wechat_redirect BioEngX 生化工程实验室 发自小木虫IOS客户端 |
回复此楼» 收录本帖的淘帖专辑推荐
 科研之家（食品） |
» 猜你喜欢
博士去二本高校当辅导员，如何调整心态？
已经有8人回复
-
27细胞生物学申博
已经有5人回复
-
面上有专家说实验设备不是我们单位的
已经有5人回复
-
江苏省自然基金 什么时候出结果
已经有6人回复
-
广西大学-广州大学招聘博士后 欢迎广大优秀人才！！！
已经有11人回复
-
闲聊
已经有3人回复
-
如何查询2026年获批项目名称？
已经有3人回复
-
两块石头
已经有10人回复
-
售SCI一区T0P文章，我:8O.55.1.O.54,科目全,可伽急
已经有15人回复
-
面上没中，邀请各位路过的虫友分析一下分数
已经有13人回复
2楼2015-10-20 11:30:41