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| Upon one-electron oxidation, this radical forms 5-OH-8-hydoxyguanine, the isomerization of which results in the formation of spiroiminodihydantoin and also in that of 5-guanidinohydantoin by loss of CO 2 depending on reaction conditions .For almost 20 years, the structure of spiroiminodihydantoin has been misassigned by Cadet et al. as 4,8-dihydro-4-hydroxy-8-oxoguanine . |
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