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| A combination of two different metabolic engineering approaches, namely the duplication of the PII biosynthetic gene cluster and systematical engineering of the cluster-situated regulatory genes, was employed in the present study to optimize PII production, which led to a maximum PII titer improvement of approximately 1.5-fold higher compared with that of the parental strain. |
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ÖÁ×ðľ³æ (ÖøÃûдÊÖ)
- ·ÒëEPI: 204
- Ó¦Öú: 103 (¸ßÖÐÉú)
- ½ð±Ò: 15293.5
- ºì»¨: 41
- Ìû×Ó: 1611
- ÔÚÏß: 431.6Сʱ
- ³æºÅ: 3856202
- ×¢²á: 2015-05-08
- ÐÔ±ð: GG
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