| 查看: 1720 | 回复: 7 | |||
| 【有奖交流】积极回复本帖子，参与交流，就有机会分得作者 学员JYzuYE 的 10 个金币 | |||
| 当前只显示满足指定条件的回帖，点击这里查看本话题的所有回帖 | |||
[交流]
JMCC reject&resubmission大家帮忙看看
|
|||
|
投心血管的JMCC 结果被reject&resubmission，编辑好像没提出什么意见。审稿人的意见感觉分歧很大啊，review1感觉并没有细看文章 连对我文章的描述都错了2处。而后2个审稿人意见还比较不错，几乎不需要补实验，只是要润色文章 答答问题。因为review1的意见改起来估计都可以发篇SCI了（见过一篇5分的文章做过上游），可能无法修改，而且我感觉他对我们有些偏见，怕是怎么改都没用。。。。请战友们分析下，重投中的可能性大么。。。。会不会换个审稿人呢，以下附审稿意见： Reviewer #1: The authorstried to show the involvement of mir-145 for CD-137 induced migration ofvascular smooth muscle cells. The concept is too complex and data qualityis not good. Composition of manuscript is not good. Manuscript included the manyof type-miss, mixed with some non-english characters. 1) Authors mentioned CD-137 down-regulate mir145, which leaded to down regulation of NFATc1 but In Fig 2A the expression ofNFATc1 with CD137 is very small. Data quality is not generally good, thus, I donot recommend the manuscript for publication. Reviewer #2: Yan et alshowed that CD137 accelerated neointima formation and VSMCs proliferation andmigration in vivo and in vitro. Mechanistically, miR145 was downregulated andresulted in increased NFATc1 expression in VSMCs upon treatment with agonisticCD137 antibody. To investigate why VSMCs phenotype transformed, the authorsshowed that overexpression of miR145 or NFATc1 deficiency could rescue the VSMCtransformation led by CD137. This is a well design and performed manuscript.There will be interesting for the readers of JMCC. However, this manuscript canbe strengthened with the following revision: Major comments Reviewer #3: The study byYan et al. showed that CD137, a protein belonging to the TNF superfamily,induces vascular smooth muscle cell dedifferentiation through down regulatingmiR-145 and up-regulating NFATc1. Previously many reports showed that miR-145could modulate the fate of smooth muscle cells In this study, the authorsshowed that miR-145 targets NFATc1 mRNA to reduces its expression, which is anovel finding. In general, the study design is logic and the data aresupporting the hypothesis. However, there are multiple issues with the study: |
回复此楼» 猜你喜欢
面上合作单位盖章
已经有5人回复
-
有多少人是今天查系统知道结果的？
已经有17人回复
-
为什么资助数各大高校都创新高，自己申请怎么就这么难
已经有8人回复
-
导师吐槽：我怎么摊上了这么个极品研究生！
已经有7人回复
-
申请删除本帖
已经有7人回复
-
基金不中，共勉
已经有10人回复
-
国自然面上复盘~欢迎讨论
已经有11人回复
-
基金未中，这种答复是模板吗？
已经有6人回复
-
看板上这么多中的，有点像50人群里49个人都是骗子的那种感觉……
已经有6人回复
-
怎么看青基中了没有啊
已经有5人回复
» 本主题相关价值贴推荐，对您同样有帮助:
- RSC “reject and resubmssion”，下次投稿是投最终状态的稿件还是投带修订模式的
已经有32人回复
- 投JMCC要求Reject & Resubmit
已经有24人回复
- Reject with encouragement for resubmission (Major revision)是啥意思啊！！
已经有12人回复
- resubmission & reject 请教大神帮忙
已经有17人回复
- reject and resubmission 大家给我看看审稿意见
已经有31人回复
- RSC杂志Reject & Resubmit 大家看看重投希望大不
已经有14人回复
- reject & resubmission 还有戏吗？
已经有16人回复
- 赞一下Journal of Materials chemistry
已经有18人回复
listensea8318
铁杆木虫 (知名作家)
- 应助: 70 (初中生)
- 金币: 1389.1
- 散金: 13314
- 红花: 15
- 帖子: 8961
- 在线: 384.9小时
- 虫号: 656999
- 注册: 2008-11-18
- 性别: GG
- 专业: 交叉学科中的光学问题
3楼2015-06-14 16:55:55
WolfYang
至尊木虫 (职业作家)
- 应助: 138 (高中生)
- 金币: 16895.4
- 红花: 11
- 帖子: 3080
- 在线: 932.3小时
- 虫号: 2496982
- 注册: 2013-06-05
- 专业: 力学中的基本问题和方法
4楼2015-06-14 19:03:33
ljq158
至尊木虫 (知名作家)
- 应助: 227 (大学生)
- 金币: 19713.2
- 散金: 2519
- 红花: 42
- 帖子: 6795
- 在线: 2093.5小时
- 虫号: 1681876
- 注册: 2012-03-11
- 专业: 化工系统工程
5楼2015-06-14 19:29:16
6楼2015-06-17 20:33:29
投票:
10