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| The permeation of PPL•HCl from gel was measured over 24 h, and plots were constructed of the cumulative corrected amounts of PPL•HCl (μg•cm-2) against time (h). The x-intercept of the extrapolated linear region gave the lag time. The slope of this linear portion of the graph provided maximum flux values at steady state (μg•cm-2•h-1). The permeation-enhancing activities were expressed as enhancement ratios of flux (ER) which were calculated by the followed equations: |
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