| 查看: 469 | 回复: 1 | |||
[求助]
求翻译，谢谢！！
|
|
Retrograde intraductal infusion of TLCS (50 μl, 3 mM) and repeated administration ofcaerulein (50 μg/injection, 12 injections) each induce acute pancreatitis that is characterized by hyperamylasemia, pancreatic edema, inflammation, and acinar cell injury/necrosis (Fig. 2Aand B). In TLCS-induced pancreatitis, hyperamylasemia, pancreatic edema, pancreaticinflammation and acinar cell injury/death are all significantly reduced (p<0.05) whenGpbar1 has been deleted (Fig. 2A) but, when pancreatitis is induced by caeruleinadministration, none of these parameters of pancreatitis severity are altered by genetic deletionof Gpbar1 (Fig. 1B). None of the features of TLCS-induced pancreatitis (i.e. hyperamylasemia,edema, and acinar cell injury/death) are observed when 50 μl of 3 mM Na-taurocholate, ratherthan TLCS, is infused into the pancreatic duct (Suppl. Fig. 2A). [ 发自手机版 https://muchong.com/3g ] |
回复此楼» 猜你喜欢
本科211，293分请求调剂
已经有6人回复
-
085600材料与化工调剂
已经有25人回复
-
本9一志愿2 0854低分专硕286求调剂
已经有4人回复
-
085600，320分求调剂
已经有9人回复
-
316求调剂
已经有5人回复
-
0856调剂
已经有8人回复
-
278求调剂
已经有5人回复
-
0703求调剂383分
已经有3人回复
-
400分求调剂
已经有3人回复
-
085701求调剂
已经有5人回复
genhunter
至尊木虫 (著名写手)
- 翻译EPI: 387
- 应助: 259 (大学生)
- 金币: 9757.4
- 散金: 10
- 红花: 60
- 帖子: 2484
- 在线: 1793小时
- 虫号: 2558361
- 注册: 2013-07-22
- 专业: 肿瘤化学药物治疗
【答案】应助回帖
★ ★ ★ ★ ★ ★ ★ ★ ★ ★
zc891101: 金币+10, ★★★★★最佳答案 2015-05-18 08:07:18
zc891101: 金币+10, ★★★★★最佳答案 2015-05-18 08:07:18
| 通过胰导管逆向灌注TLCS (50μl,3毫摩尔)和雨蛙肽重复处理(50μg /注射,注射12次)都可以诱发具有血淀粉酶过多、胰腺水肿和炎症、以及腺泡细胞损伤和坏死特征的急性胰腺炎(图2 A和B)。在Gpbar1基因敲除的动物中用TLCS诱发的胰腺炎, 血淀粉酶过多, 胰腺水肿、胰腺腺泡细胞炎症和损伤/死亡都显著降低(p < 0.05) (图2), 但雨蛙肽重复处理后引起的胰腺炎的个体中这些参数不因为Gpbar1基因的敲除与否有明显差异(图1 B)。通过胰导管逆向灌注50μl ,3毫摩尔牛磺酸钠不引起任何像TLCS-i诱发胰腺炎的病征(即h血淀粉酶过多、水肿和腺泡的细胞受伤或死亡) (补充材料，图2)。 |
2楼2015-05-17 08:16:22
