| 查看: 127 | 回复: 0 | |||
| 当前主题已经存档。 | |||
[交流]
Sanofi Obesity Drug Gets Final Okay From UK's NICE
|
|||
|
LONDON (Reuters) Jun 25 - Sanofi-Aventis won a final green light for its obesity drug Acomplia (rimonabant) from Britain's cost-effectiveness watchdog NICE on Wednesday, clearing the way for doctors to prescribe it on the state health service. The move was expected following a positive appraisal from the National Institute for Health and Clinical Excellence (NICE) in March. It marks a small positive for the French drugmaker's once much-hyped medicine, which has failed to live up to early expectations. NICE's final guidance recommends using Acomplia as an addition to diet and exercise for obese or overweight adults who don't respond to or are intolerant of two other weight-loss drugs, orlistat and sibutramine. But NICE cautioned that treatment should not continue beyond 6 months unless patients lost at least 5 percent of their initial body weight and there should, in any event, be a formal clinical assessment after 2 years. The UK decision contrasts with Germany where Acomplia is not reimbursed by health insurers because it is deemed simply to improve lifestyle. Acomplia was once touted as a multibillion-dollar seller, but hopes for the product dimmed last year when a U.S. expert panel recommended against its approval in the world's biggest market, after it was linked to rare cases of suicidal thoughts. Sanofi said in October it expected only limited sales of the drug in the next few years, until new clinical trial results testing it in diabetes are ready for submission to regulators in 2009. Worldwide sales of the drug were a meagre 79 million euros ($122.9 million) last year. Roche makes the older weight-loss drug orlistat under the brand name Xenical, while sibutramine is marketed by Abbott Laboratories under the brand names Meridia or Reductil. |
回复此楼» 猜你喜欢
070700求调剂
已经有1人回复
-
求调剂总分327
已经有1人回复
-
药物学论文润色/翻译怎么收费?
已经有111人回复
-
考研调剂：国家蛋白质科学中心（国家重点实验室）和安徽医科大学基础医学院联培
已经有4人回复
-
华南理工大学 基础医学学硕和临床医学学硕调剂
已经有11人回复
-
BL21(DE3)UV或者丝裂霉素诱导条件下会释放DE3的噬菌体吗？
已经有14人回复
-
北京协和医学院杰青课题组招聘科研助理
已经有0人回复
-
北京协和医学院杰青课题组招聘科研助理
已经有0人回复
-
求助中国药典1995年版、二部
已经有0人回复
-
北京协和医学院杰青课题组招聘科研助理
已经有0人回复
