|
|
[求助]
求助精确的，专业的英语翻译，求大师翻译，万分谢谢
|
Chemistry, traditionally being the science of synthesis and structural manipulations of molecules, has gradually undertaken the more challenging task of biology-oriented synthesis. The generation of molecules/molecular assemblies possessing welldefined biological functions remains an extremely challenging task; immediate refinements in conventional synthetic tactics are necessary. New and more efficient chemical reactions and methodologies, which may override the laborious protection/deprotection and purification steps in conventional total synthesis, could revolutionize the next-generation chemical and biological research. A set of chemical reactions, known as bioorthogonal reactions, that are orthogonal to most functional groups in biological systems has so far shown promising applications in biological research. Of these reactions, the Cu(I)-catalyzed version of the Huisen 1,3-dipolar cycloaddition reaction between azides and terminal alkynes for the construction of trizoles, referred to as a “click chemistry reaction”, was defined by nobel laureate KB Sharpless and associates in 2001. Click chemistry has recently emerged to become one of the most powerful tools in drug discovery, chemical biology, and proteomic applications. In recent years, the design and synthesis of pharmacologically relevant heterocyclic molecules by combinatorial techniques have proven to be a promising strategy in the search for new pharmaceutical lead structures. Click chemistry is one of the powerful reactions for making carbon−heteroatom−carbon bonds in aqueous environment with a wide variety of chemical and biological applications in various fields. |
» 猜你喜欢
售SCI-T0P文章，我:8O.5.5.1.O.54,科目齐全,可+急
已经有6人回复
-
售一区SCI文章T0P，我:8O.551.O54,科目全,可十急
已经有9人回复
-
售SCI-T0P文章，我:8O.5.5.1.O.54,科目齐全,可+急
已经有3人回复
-
考博求助
已经有3人回复
-
售SCI一区文章，我:8.O.551.O.5.4,科目全,可伽急
已经有5人回复
-
售SCI一区T0P文章，我:8.O.55.1.O.5.4,科目全,可+急
已经有4人回复
-
售SCI一区T0P文章，我:8.O.55.1.O.5.4,科目全,可+急
已经有5人回复
-
售SCI-T0P文章，我:8O.5.5.1.O.54,科目齐全,可+急
已经有9人回复
-
售一区SCI文章T0P，我:8O.551.O54,科目全,可十急
已经有9人回复
-
售SCI一区T0P文章，我:8.O.55.1.O.5.4,科目全,可+急
已经有10人回复
|
回复此楼
10