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[资源] Adv. Mater.最新综述：功能化超分子聚合物及其在生物医学方面的应用

本综述详细介绍了功能化超分子聚合物的设计与合成（包括非共价相互影响，拓扑结构等），性质与功能（水的相容性，生物降解和生物相容性，刺激响应性，靶向性，生物活性，功能化等），生物医学方面的应用（药物传递，基因转染，蛋白质传递，生物影像和诊断，组织工程学，仿生化学等），为功能化超分子聚合物的研究提供了积极的指导作用。
Functional Supramolecular Polymers for Biomedical Applications 共29页引文353篇
Ruijiao Dong, Yongfeng Zhou, Xiaohua Huang, Xinyuan Zhu,* Yunfeng Lu, and Jian Shen*
Dr. R. J. Dong, Prof. Y. F. Zhou, Prof. X. Y. Zhu, Prof. Y. F. Lu
School of Chemistry and Chemical Engineering
State Key Laboratory of Metal Matrix Composites, Shanghai Jiao Tong University,800 Dongchuan Road  , Shanghai 200240  , PR China
E-mail:  xyzhu@sjtu.edu.cn                                                                                                                                                                            Prof. X. H. Huang, Prof. J. Shen
Jiangsu Collaborative Innovation Center of Biomedical Functional Materials
Jiangsu Key Laboratory of Biomedical Materials
College of Chemistry and Materials Science
Nanjing Normal University, Nanjing 210046  , PR China
E-mail:  shenjianbio@hotmail.com
Prof. Y. F. Lu
Department of Chemical and Biomolecular Engineering
University of California , Los Angeles  , California 90095  , USA

As a novel class of dynamic and non-covalent polymers, supramolecular polymers not only display speciﬁ c structural and physicochemical properties, but also have the ability to undergo reversible changes of structure, shape, and function in response to diverse external stimuli, making them promising candidates for widespread applications ranging from academic research to industrial ﬁ elds. By an elegant combination of dynamic/reversible structures with exceptional functions, functional supramolecular polymers are attracting increasing attention in various ﬁ elds. In particular, functional supramolecular polymers offer several unique advantages, including inherent degradable polymer backbones, smart responsiveness to various biological stimuli, and the ease for the incorporation of multiple biofunctionalities (e.g. ,  targeting and bioactivity), thereby showing great potential for a wide range of applications in the biomedical ﬁ eld. In this Review, the trends and representative achievements in the design and synthesis of supramolecular polymers with speciﬁ c functions are summarized, as well as their wide-ranging biomedical applications such as drug delivery, gene transfection, protein delivery, bio imaging and diagnosis, tissue engineering, and biomimetic chemistry. These achievements further inspire persistent efforts in an emerging interdisciplin ary research area of supramolecular chemistry, polymer science, material science, biomedical engineering, and nanotechnology.

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