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急求助：关于脂质体体外释放，漏槽条件
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英文投稿，专家意见如下 我想问一下，我应该如何回答这个问题，应提供什么数据和内容？ Sink conditions: In vitro release studies with dialysis system is very difficult to conduct in sink conditions. If the donor compartment has not a sufficient volume it is not in sink conditions. Please provide information to show that both donor and receiver compartments are in sink conditions. Additional in vitro experiments should be conducted in a sink, the fraction being released from the liposomes can be separated by high speed centrifugation of the liposomes and docetaxel assay in the supernatant. |
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