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虫号: 2327439
注册: 2013-03-07
专业: 有机合成

[交流] 中国科学院过程工程研究所糖生物工程课题组招聘联合培养硕士研究生2名

中国科学院过程工程研究所糖生物工程课题组招聘联合培养硕士研究生2名

课题方向：酶学与蛋白质工程。

一、基本要求：
1、生物化学与分子生物学专业；
2. 基础知识扎实，对科研工作有浓厚兴趣，自我管理和自我约束能力强，有吃苦耐劳精神；
3、除完成学位论文外，还需至少发表1篇SCI论文（保证发表文章的质量可达到原学校的毕业要求）；
4、在研究所全日制工作时间不低于18个月；
5、事先已征得所在学校导师的同意。

二、工作职责：
根据要求开展相关研究工作，完成项目试验和测试。

三、待遇：
（1）与本单位联合培养学生福利一致（助学津贴+午餐补助），待遇从优；
（2）提供住宿条件。详情面谈。

四、地址：
北京市海淀区中关村北二条1号。

本课题组科研氛围浓厚，资源充足。一经录取将给予充分的指导，是一个良好的学习平台。欢迎有意者发送简历。

联系人：李老师
邮箱： jjli@ipe.ac.cn

代表性文章:

1. Wang, Q, Huang, X, Zhang, J, Lu, X, Li, S, Li, J-J*, “Engineering self-sufficient aldehyde deformylating oxygenase fused to alternative electron transfer systems for efficient conversion of aldehydes into alkanes”, Chem. Commun., 2014, 50, 4299-4301. (IF 6.378)
2. Zhang, J, Lu, X, Li, J-J*, “Conversion of fatty aldehydes into alk(a/e)nes by in vitro reconstituted cyanobacterial aldehyde deformylating oxygenase with a cognate electron transfer system”, Biotechnol. Biofuels, 2013, 6, 86. (IF 5.552)
3. Bao, X, Huang, X, Lu, X, Li, J-J*, “Improvement of H2O2 stability of Pleurotus eryngii versatile peroxidise through rational protein engineering”, Enzyme Microb. Tech., 2014, 54, 51-58. (IF 2.592)
4. Huang, X, Lu, X, Li, J-J*, “Cloning, characterization and application of a glyceraldehyde-3-phosphate dehydrogenase promoter from Aspergillus terreus”, J. Ind. Microbiol. Biot., 2014, 41, 585-592 (IF 2.321).
5. Bao, X, Liu, A, Lu, X, Li, J-J*, “Direct over-expression, characterization and H2O2 stability study of active Pleurotus eryngii versatile peroxidase in Escherichia coli”, Biotechnol. Lett., 2012, 34, 1537-1543. (IF 1.853)
6. Li, J-J, Bugg, TDH*, “Investigation of a general base mechanism for ester hydrolysis in C–C hydrolase enzymes of the α/β-hydrolase superfamily: a novel mechanism for the serine catalytic triad”, Org. Biomol. Chem., 2007, 5, 507-513. (IF 3.569)
7. Li, J-J, Li, C, Blindauer, CA, Bugg, TDH*, “Evidence for a gem-diol reaction intermediate in bacterial C-C hydrolase enzymes BphD and MhpC from 13C NMR spectroscopy”, Biochemistry, 2006, 45, 12461–12469. (IF 3.377)
8. Li, J-J, Bugg, TDH*, “Stereochemistry of the reaction catalysed by 2-hydroxy-6-keto-6-phenyl-hexa-2,4-dienoic acid 5,6 hydrolase (BphD)”, Chem. Commun., 2005, 130-132. (IF 6.378)
9. Li, J-J, Bugg, TDH*, “A fluorescent analogue of UDP-N-acetylglucosamine: application for FRET assay of peptidoglycan translocase II (MurG)”, Chem. Commun., 2004, 182-183. (IF 6.378)
10. Sergeant, M, Li, J-J, Fox, C, Brookbank, N, Rea, D, Bugg, TDH*, Thompson, AJ*, “Selective Inhibition of Carotenoid Cleavage Dioxygenases, Phenotypic Effects on Shoot Branching”, J. Biol. Chem., 2009, 284, 5257-5264. (IF 4.651)
11. Li, C, Li, J-J, Montgomery, MG, Wood, SP, Bugg, TDH*, “Catalytic role for arginine 188 in the C-C hydrolase catalytic mechanism for Escherichia coli MhpC and Burkholderia xenovorans LB400 BphD”, Biochemistry, 2006, 45, 12470–12479. (IF 3.377)

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