| 查看: 753 | 回复: 6 | ||
| 本帖产生 1 个 翻译EPI ，点击这里进行查看 | ||
[求助]
关于药动学里方法学的一段话，不太懂
|
||
|
Linearity of calibration curves, LLOD and LLOQ LLOQ can be quantitated with accuracy within 15% of nominal and precision not exceeding 15% CV, and was 4.0 ng/mL for TB-II and 3.9 ng/mL for TA-III. LLOD of TB-II and TA-III was obtained when the solution was diluted to 1.8 ng/mL and 1.6 ng/mL, respectively, and the signal-to-noise ratio was 2-fold. The calibration curve of TB-II was y = 0.3379x + 0.02973 (r = 0.9978) and was y = 1.778x−0.02613(r = 0.9989) for TA-III. The difference between the nominal standard concentration and the back-calculated concentration from the weighed linear regression line was varied from−4.3% to 4.6% for each point on the standard curve (CV varied from 1.7% to 8.2%). Carry-over was tested by injecting two processed blank matrix samples subsequently after injection of an ULOQ (the upper limit of quantification) sample in three independent runs.The response in the first blank matrix at the retention time of the analytes should be less than 20% of the mean response of a LLOQ sample for the analytes. The response in the first blank matrix at the retention time of the analytes was less than 7% of the mean response at the LLOQ for TA-III and 3% for TB-II. Therefore, the carry-over test was found to be acceptable. |
回复此楼» 猜你喜欢
288求调剂
已经有6人回复
-
复试调剂
已经有12人回复
-
计算机11408，286分求调剂
已经有3人回复
-
材料专硕322分
已经有8人回复
-
一志愿上海海洋大学083200食品学硕，求调剂，接受其他专业083200
已经有5人回复
-
081200-11408-276学硕求调剂
已经有5人回复
-
材料调剂
已经有10人回复
-
313求调剂
已经有7人回复
-
304求调剂（085602，过四级，一志愿985）
已经有14人回复
-
材料工程302分求调剂
已经有7人回复
RXMCDM
版主 (文坛精英)
- 翻译EPI: 530
- 应助: 401 (硕士)
- 贵宾: 1.908
- 金币: 38947.6
- 散金: 4908
- 红花: 88
- 沙发: 4
- 帖子: 11453
- 在线: 1355.6小时
- 虫号: 2739168
- 注册: 2013-10-20
- 性别: GG
- 专业: 一般管理理论与研究方法论
- 管辖: 论文翻译
【答案】应助回帖
★ ★ ★
weercog: 金币+3, 翻译EPI+1, ★★★很有帮助 2014-05-14 17:53:24
weercog: 金币+3, 翻译EPI+1, ★★★很有帮助 2014-05-14 17:53:24
|
Carry-over was tested by injecting two processed blank matrix samples subsequently after injection of an ULOQ (the upper limit of quantification) sample in three independent runs. 携带污染测试：三次独立测试，加入定量测定的最大上限样本后，加入两个经过处理的空白基质样品。 |
2楼2014-05-13 21:59:13
RXMCDM
版主 (文坛精英)
- 翻译EPI: 530
- 应助: 401 (硕士)
- 贵宾: 1.908
- 金币: 38947.6
- 散金: 4908
- 红花: 88
- 沙发: 4
- 帖子: 11453
- 在线: 1355.6小时
- 虫号: 2739168
- 注册: 2013-10-20
- 性别: GG
- 专业: 一般管理理论与研究方法论
- 管辖: 论文翻译
3楼2014-05-13 22:03:29
4楼2014-05-14 17:54:37
RXMCDM
版主 (文坛精英)
- 翻译EPI: 530
- 应助: 401 (硕士)
- 贵宾: 1.908
- 金币: 38947.6
- 散金: 4908
- 红花: 88
- 沙发: 4
- 帖子: 11453
- 在线: 1355.6小时
- 虫号: 2739168
- 注册: 2013-10-20
- 性别: GG
- 专业: 一般管理理论与研究方法论
- 管辖: 论文翻译
5楼2014-05-14 18:04:45
6楼2014-05-14 21:17:32
RXMCDM
版主 (文坛精英)
- 翻译EPI: 530
- 应助: 401 (硕士)
- 贵宾: 1.908
- 金币: 38947.6
- 散金: 4908
- 红花: 88
- 沙发: 4
- 帖子: 11453
- 在线: 1355.6小时
- 虫号: 2739168
- 注册: 2013-10-20
- 性别: GG
- 专业: 一般管理理论与研究方法论
- 管辖: 论文翻译
7楼2014-05-14 21:26:44
