|
|
【答案】应助回帖
★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ...
ouyiji017: 金币+70, 翻译EPI+1, ★★★★★最佳答案, 呵呵，非常感谢！ 2014-05-09 10:08:22
Abstract : Morita-Baylis-Hillman (MBH) reaction is a kind of effective synthesis reaction of carbon - carbon bond formation to generate multiple functional group molecules which has absorbed more and more attention of chemists of various field since 1980s. Being the polyfunctional compound formation reaction of aldehyde and active polyene,MBH reaction is characterized with the basic features of high efficient synthetic methods such as reaction selectivity ( chemical , regional , diastereomeric and mapped ) , atom economy , mild reaction conditions and the product have many functional groups which can further convert to other groups . Many published high level review articles after the year of 2000 indicated the great expectation and development potential of MBH reaction in organic synthesis. Recently , studies of the reaction , in particular small molecule -catalyzed MBH reaction is very active .Hower , MBH reaction has its own drawbacks, such as slow reaction rate , lower conversion efficiency , fewer reaction substrates . To overcome these shortcomings , a two-step reaction of aldehydes derived MBH carbonate was invesgated ,which is the fundamental research of further MBH allyl carbonate alkylation study.
Keywords : MBH reaction ;asymmetric organocatalysis |
|
回复此楼