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Injections Animals were divided into three groups (n = 6/group), and received intraperitoneal  injection of either saline (control) or 10, or 40 mg/kg dose of resveratrol .

Acute behavioral tests were conducted 20 min after first injection.

For chronic behavioral tests the same animals continued receiving daily injection for 7 days, and behavioral tests were carried out 18–20 h after the last injection.

Following 1 week of rest after the last chronic injection animals were tested again for possible lasting behavioral effects.Following this behavioral test, the animals were rested for 10 days before receiving another 7 days of chronic injection.

In this case,however, the animals were sacrificed by decapitation, 18–20 h after last injection, without any behavioral tests to collect brains for neurochemical evaluations.

Thus, the same animals were used to assess the behavioral and neurochemical effects of resveratrol .
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