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lh_imm

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[求助] 求翻译一段话 请在晚八点前应助 不胜感激 谢谢

本课题拟在前期工作基础上,以ss6为突破口,并利用固相dcs获取dcs的相互作用分子,以期系统阐明dcs调控人胶质瘤细胞凋亡的分子机制,明确dcs在介导人胶质瘤细胞凋亡过程中的功能及意义;同时,在荷瘤动物模型上,研究dcs原位给药对在体胶质瘤的作用,系统评价dcs间质化疗给药治疗脑胶质瘤的效果。为dcs介导胶质瘤细胞凋亡的分子机制新认识提供实验依据,同时为解决限制抗肿瘤SSD成药性与其新药研发的作用机制不清和溶血毒副作用等问题提供有价值的资料和借鉴
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RXMCDM

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真强必胜: 金币+2, 好 2014-03-07 12:28:59
This  project   will  take ss6 as a breakthrough and use solid-phase dcs to get  interaction molecules of dcs on the basis of the preliminary work   to clarify the molecular mechanisms of apoptosis  of  dcs regulated  human glioma  cells ,  especially to explicit the  function and significance of  dcs  in mediating human glioma   apoptosis in tumor .  At  the  same time,   in vivo situ chemotherapy administration role of  glioma will be studied in tumor-bearing animal models to systematically evaluate the effect  of dcs interstitial chemotherapy administration treatment of  cerebral gliomas .  It will provide new  experimental evidence for  the understanding of molecular mechanisms of dcs-mediated  glioma apoptosis  and  valuable information and reference  to overcome   the limitations of unclear mechanism of   antitumor SSD druggability, unclear mechanism of  new  anti-tumor drug evolved in  drug development, hemolytic toxicity ,etc.
2楼2014-03-06 17:26:55
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