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| This suggests that the effects of Notch decoy differs from the effects on angiogenesis following the sole inhibition of Dll4¨CNotch signaling, perhaps reflecting that, in this case, Jagged1 was also blocked. These stud-ies emphasize that blocking Notch signaling is appealing as an alternative antiangiogenic strat-egy. For instance, we refer back to the observation in breast cancer, in which high levels of Notch1 have been shown to promote tumorigenesis. |
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yin198716: ½ð±Ò+5, ·ÒëEPI+1 2014-02-23 12:56:48
yin198716: ½ð±Ò+5, ·ÒëEPI+1 2014-02-23 12:56:48
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