24小时热门版块排行榜    

查看: 357  |  回复: 1
本帖产生 1 个 翻译EPI ,点击这里进行查看

yin198716

新虫 (正式写手)

[求助] 翻译求助

This suggests that the effects of Notch decoy differs from the effects on angiogenesis following the sole inhibition of Dll4–Notch signaling, perhaps reflecting that, in this case, Jagged1 was also blocked. These stud-ies emphasize that blocking Notch signaling is appealing as an alternative antiangiogenic strat-egy. For instance, we refer back to the observation in breast cancer, in which high levels of Notch1 have been shown to promote tumorigenesis.
Oncology
已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖

RXMCDM

版主 (文坛精英)

优秀版主优秀版主优秀版主

【答案】应助回帖

★ ★ ★ ★ ★
yin198716: 金币+5, 翻译EPI+1 2014-02-23 12:56:48
以上所述表明,假性Notch 的作用不同于单独抑制Dll4-Notch信号的血管生成作用,这种情况下可能反映出agged1也被阻断了。这些研究着重表明,阻断Notch信号是极具吸引力的抗血管生成替代方法。举例来说,我们回到在乳腺癌所观察到的,乳腺癌高水平的Notch1已证明能促进肿瘤发生。
供参考。
2楼2014-02-19 20:10:50
已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖
相关版块跳转 我要订阅楼主 yin198716 的主题更新
信息提示
请填处理意见