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annieyaya

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preexisting functional abilities such as mobility,respiratory function,skin integrity,and nutritional status establish patients'performance condition.Tools such as the Karnofsky, World Heath Organization,and Zubrod scales objectively measure functional abilities.Howerer,the scales measure only physical functional abilities of atients.

For patients who recur after initial therapy,response to additional chemothepapy seems to be directly related to the platinum-free interval,which is the time elapsed since the completion of platinum-based therapy without recurrence.Some will be retreated with previously demonstrated tumor-sensitive regimes as well as new drugs in novel combinations or delivery modalities.Responses to subsequent treatments can vary ased on the intensity of previous side effects and residual sequelae.

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