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蛋白-无机杂化纳米花 发表在Nature上
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《蛋白-无机杂化纳米花》(Protein inorganic hybrid nanoflowers)是清华大学发表在纳米技术领域国际顶尖学术期刊Nature Nanotechnology上的一篇文章,提出了一种合成含酶杂化纳米花的新方法,并结合生物催化实验证实了纳米花结构能够有效提高酶分子的体外催化活性和催化稳定性。该项成果为进一步研究生物催化用酶的人工设计和改造提供了重要的新方法。该项成果中,酶分子和无机纳米材料之间的协同作用使得含酶纳米花具有远高于一般固定化酶的催化活性和稳定性。成果中所展示的具有高催化活性和稳定性的酶-无机纳米花可应用于构建各种新型的功能性蛋白-无机纳米结构,在生物传感器、生化分析器件、生物燃料电池和工业生物催化等领域有着重要的潜在应用价值。 Flower-shaped inorganic nanocrystalshave been used for applications in catalysis and analytical science, but so far there have been no reports of ‘nanoflowers’ made of organic components. Here, we report a method for creating hybrid organic–inorganic nanoflowers using copper (II ) ions as the inorganic component and various proteins as the organic com-ponent. The protein molecules form complexes with the copper ions, and these complexes become nucleation sites for primary crystals of copper phosphate. Interaction between the protein and copper ions then leads to the growth of micrometre-sized particles that have nanoscale features and that are shaped like flower petals. When an enzyme is used as the protein com-ponent of the hybrid nanoflower, it exhibits enhanced enzy-matic activity and stability compared with the free enzyme. This is attributed to the high surface area and confinement of the enzymes in the nanoflowers.欢迎大家订阅我的专辑“小木虫上最有价值的资源宝库” http://muchong.com/bbs/taotie.php?action=view&ttid=47051 http://muchong.com/bbs/taotie.php?action=view&ttid=47307 所列资源基本都是高亮三级精华帖,非常有收藏价值! 欢迎大家积极订阅,资源不断更新。。。 补充文献: http://muchong.com/bbs/viewthread.php?tid=6676253&fpage=1 http://muchong.com/bbs/viewthread.php?tid=6623675 http://muchong.com/bbs/viewthread.php?tid=6641097&fpage=3 http://muchong.com/bbs/viewthread.php?tid=6626789 http://muchong.com/bbs/viewthread.php?tid=6626709 要想得到以上效果必学的绘图软件: http://muchong.com/bbs/viewthread.php?tid=6503162 http://muchong.com/bbs/viewthread.php?tid=6454237 http://muchong.com/bbs/viewthread.php?tid=6594617 http://muchong.com/bbs/viewthread.php?tid=5473255&fpage=2 http://muchong.com/bbs/viewthread.php?tid=6594638 http://muchong.com/bbs/viewthread.php?tid=6610009 http://muchong.com/bbs/viewthread.php?tid=6594698 [ Last edited by Jeaweal on 2013-12-4 at 13:07 ] |
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