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To model DNA, we assume the charge per unit length is ¦Ë, which is about one negative charge per 1.7Åof length. For simplicity,we assume that DNA is a long, charged, cylindrical molecule. The cylinder diameteris about 20 Å. The electrical field of a long strand of DNA in water depends on the perpendicular distance r from the strand and on ¦Ë.The electric field lines must point inward because DNA is negatively charged.Denoting the electric field at a distance r from the cylinder by E(r), we observe that it is inversely proportional to the dielectric constant  and inversely proportional to some power, say r¦Á, of r, hence we write:
E(r) = const k*¦Ë/¦Å*r¦Á     (2.27)
In vacuum, the electric field of a monopole of charge Q a distance R away is kQ/R2.
Since ¦Ë is a charge per unit length, ¦Á = 1, hence:
E(r) = 2 k*¦Ë/¦Å*r    (2.28)
Since E(r) = −dV/dr, we have an equivalent form of Equation (2.28).
dV (r)/dr= −2k*¦Ë/¦Å*r      (2.29)
Integrating Equation (2.29), we see that:
V (r) = −2k*¦Ë*ln r/¦Å + k0      (2.30)
In Equation (2.30), k0 is a constant conveniently chosen to be zero.
Suppose a positive monovalent ion moves in from a distance of 1¦Ìm to the surface
of the DNA. The work done or W will be:
W = |e |V (r = 1¦Ìm) − |e|V (r = 10Å    (2.31)
Hence:
W =  10 ¡¤ 2 ¡¤ 10−20J   (2.32)
Using k = 8.99 ¡Á 109 m2/C2,  = 80.4, ¦Ë = −|e| per 1.7 ¡Á 10−10m, and e = 1.6 ¡Á
10−19C from Equation    (2.32)

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