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Single Molecule Detection in Solution.pdf
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Single-Molecule Detection in Solution Methods and Applications By Publisher: Wiley-VCH Number Of Pages: 400 Publication Date: 2002-01-15 ISBN / ASIN: 3527403108 EAN: 9783527403103 Publisher: Wiley-VCH Number Of Pages: 400 Publication Date: 2002-01-15 Sales Rank: 1762785 ISBN / ASIN: 3527403108 Book Description: The detection of single molecules opens up new horizons in analytical chemistry, biology and medicine. This discipline, which belongs to the expanding field of nanoscience, has been rapidly emerging over the last ten years. This handbook provides a thorough overview of the field. It begins with basics of single molecule detection in solution, describes methods and devices (fluorescense correlation spectroscopy, surface enhanced Raman scattering, sensors, especially dyes, screening techniques, especially confocal laser scanning microscopy). In the second part, various applications in life sciences and medicine provide the latest research results. This modern handbook is a highly accessible reference for a broad community from advanced researchers, specialists and company professionals in physics, spectroscopy, biotechnology, analytical chemistry, and medicine. Written by leading authorities in the field, it is timely and fills a gap - up to now there exists no handbook concerning this theme. Table of Contents Obituary List of Contributors 1 Single Molecule Detection in Liquids and on Surfaces under Ambient Conditions: Introduction and Historical Overview 1 2 Theoretical Foundations of Single Molecule Detection in Solution 21 3 Conceptual Basis of Fluorescence Correlation Spectroscopy and Related Techniques as Tools in Bioscience 69 4 Surface-enhanced Raman Scattering (SERS) - A Tool for Single Molecule Detection in Solution 121 5 Single Molecule Detection on Surfaces with the Confocal Laser Scanning Microscope 145 6 Spectroscopy of Individual Photosynthetic Pigment-Protein Complexes 185 7 Single Dye Tracing for Ultrasensitive Microscopy on Living Cells 231 8 Single Molecule Identification in Solution: Principles and Applications 247 9 Studying Molecular Motors on the Single Molecule Level 273 10 The Chemistry of a Single Enzyme Molecule 293 11 Single Molecule Detection of Specific Nucleic Acid Sequences 303 12 Single Molecule Detection in the Near-infrared 323 Name Index 363 Subject Index 365 http://www.fs2you.com/files/4606272e-96b0-11dc-8806-00142218fc6e/ |
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