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Mosaic analysis has demonstrated that Notch is required cell-autonomously for stalk cell specification by actively repressing tip cell phenotypes [ Last edited by cainiaodui on 2013-8-29 at 14:13 ] |
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cainiaodui: 金币+5, 翻译EPI+1 2013-08-29 21:18:17
cainiaodui: 金币+5, 翻译EPI+1 2013-08-29 21:18:17
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嵌合分析实验表明柄细胞自主特化的过程中需要Notch信号途径来积极地抑制尖细胞表现型 补充： ；嵌合分析 Mosaic analysis https://www.eoechina.com.cn/notice-details-3794.html https://www.ebiotrade.com/newsf/2011-8/2011811113335482.htm https://www.ebioservice.com/show_news.asp?id=1367 ；表现型 =表型=phentype ；phenotype, phenotype all the observable characteristics of an organism, such as shape, size, colour, and behaviour, that result from the interaction of its genotype基因型 (total genetic inheritance) with the environment. The common type of a group of physically similar organisms is sometimes also known as the phenotype. The phenotype may change constantly throughout the life of an individual because of environmental changes and the physiological and morphological changes associated with aging. Different environments can influence the development of inherited traits (as size, for example, is affected by available food supply) and alter expression by similar genotypes (for example, twins maturing in ... (100 of 142 words) ；cell autonomously 细胞自主 https://www.nibs.ac.cn/index.php?act=view&id=2786 ；尖端细胞 (tip cell)和 柄细胞 (stalk cell) https://cjbmb.bjmu.edu.cn/CN/abstract/abstract19392.shtml ；DLL4/Notch信号通路在肿瘤血管芽生过程中作用研究进展 ；（de facto，拉丁语，指虽法律上站不住，但事实上却为人所承认） https://www.ebiotrade.com/newsf/2008-8/200884153107.htm ；血管内皮生长因子（英文：vascular endothelial growth factor，简称：VEGF），早期亦称作血管通透因子（英文： vascular permeability factor，简称：VPF)，是对血管内皮细胞具有特异性的肝素结合生长因子（heparin-binding growth factor），可在体内诱导血管新生（induce angiogenesis in vivo）。 https://zh.wikipedia.org/zh-cn/% ... F%E5%9B%A0%E5%AD%90 ；Vascular endothelial growth factor (VEGF) is a signal protein produced by cells that stimulates vasculogenesis and angiogenesis血管发生和发展. It is part of the system that restores the oxygen supply to tissues when blood circulation is inadequate. Serum concentration of VEGF is high in bronchial asthma and low in diabetes mellitus. VEGF's normal function is to create new blood vessels during embryonic development, new blood vessels after injury, muscle following exercise, and new vessels (collateral circulation) to bypass blocked vessels ；Vasculogenesis and Angiogenesis Vasculogenesis is the process of new blood vessel formation during embryonic development of the cardiovascular system. This is followed by formation of a vascular tree and finally the cardiovascular system with the myriad of blood essels that nourish all tissues and organs. Angiogenesis, on the other hand is the process by which new blood vessels take shape from existing blood vessels by "sprouting" of endothelial cells thus expanding the vascular tree. Both scenarios are based on activation, migration, proliferation and maturation of unique precursor cells. https://www.intechopen.com/books ... generative-medicine 在多种细胞的特化（specification）中起关键作用的传导细胞间相互作用信号的途径, 称为Notch信号途径[1] https://baike.baidu.com/view/575908.htm https://www.dls.ym.edu.tw/lesson3/org1.htm Notch 信号途径的字面意思；Notch基因最早发现于果蝇，部分功能缺失导致翅缘缺刻（notches）。 https://www.baike.com/wiki/Notch ... 7%E9%80%94%E5%BE%84 |
2楼2013-08-29 17:49:07
cainiaodui
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3楼2013-08-29 21:18:43