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[原创翻译]中年女性比男性有更高的罹患中风病危险
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NEUROLOGY 2007;69:1898-1904 © 2007 American Academy of Neurology A midlife stroke surge among women in the United States Background: We assessed sex differences in stroke prevalence among individuals of midlife age (35 to 64 years) in the United States and determined factors predicting stroke. 背景：评估美国中年人（35到64岁）中风病流行特点的性别差异与预测因素。 Methods: Data from 1999 to 2004 (n = 17,061) from the National Health and Nutrition Examination Survey, a nationally representative sample of US adults, were used to assess sex differences in stroke prevalence and to identify independent predictors of stroke occurrence among middle-aged individuals. 方法：数据来源于一项名为“国家健康与营养调查研究”的美国成年人抽样调查，以评估中年个体中风病流行特点的性别差异和确定中风病独立预测因素。 Results: Women aged 45 to 54 years had significantly higher odds of having experienced a stroke vs men of the same age (odds ratio [OR] 2.39, 95% CI 1.32 to 4.32). 结果：45到54岁之间的女性比同年龄组男性有更高的患中风病的几率。 No other significant midlife stroke differences between sexes were noted. 未发现其他有意义的差异。 A higher stroke trend was seen in 45- to 54-year-old women vs 35- to 44-year-old women (OR 2.13, 95% CI 0.95 to 4.80, p = 0.067), but no difference was seen in stroke rates in 55- to 64-year-old women vs 45- to 54-year-old women (OR 1.40, 95% CI 0.6912 to 2.8229, p = 0.352). 45到54岁的女性比35到44岁的女性有更高的患中风病的趋势，但与55到64岁的女性相比未见差异。 Independent predictors of stroke in women aged 45 to 54 years were coronary artery disease (OR 12.790, 95% CI 1.901 to 86.063, p = 0.009) and waist circumference (OR 1.543, 95% CI 1.002 to 2.376, p = 0.049). 45到54岁女性的中风病独立预测因素为冠心病和腰围。 Several vascular risk factors including systolic blood pressure and total cholesterol levels increased at higher rates among women compared with men in each successively older cohort from 35 to 64 years. 在35到64岁的每一个连续年龄组内，包括收缩压和总胆固醇水平在内的血管危险因素均较男性有更高的发生率。 Conclusions: A higher prevalence of stroke may exist among women aged 45 to 54 years compared with similarly aged men. 结论：45岁到54岁的女性较同年龄组男性有更高的中风病流行率。 This potential disparity could be due in part to inadequate stroke risk factor modification in women and is deserving of further study. 这一潜在的差异应该有助于修订女性中风病危险因素（这句翻译的对吗？）而且值得进一步研究。 |
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