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moyamoya665

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[交流] 深海鱼油:缓解狼疮

Fish Oil Supplements May Ease Lupus
深海鱼油:缓解狼疮
Nov. 7, 2007 (Boston) -- Fish oil supplements may help improve the symptoms
of lupus, according to new research presented at the American College of
Rheumatology's annual meeting. What's more, the supplements also improve blood
flow and blood vessel function in people with lupus who are known to be at
increased risk for heart disease.
2007年11月7日(波士顿)――据美国风湿病学会年会上的一项新研究称,补充鱼油可
能会改善狼疮症状。另外,补充鱼油也能改善狼疮患者的血液流动及血管功能,该类
患者心脏病风险较高。
Lupus is an autoimmune disorder that occurs when the body engages in friendly
fire against its own tissues and organs including the skin, joints, kidneys
, brain, heart, lungs, and blood. It affects close to 1.5 million Americans
, according to the SLE Lupus Foundation in New York City.
狼疮是一种自身免疫性疾病,当身体出现对抗自身组织和器官(包括皮肤、关节、肾
脏、大脑、心脏、肺和血液)的轻微炎症时该病发作。据纽约红斑狼疮基金的调查结
果显示,美国约有50万人患此病。
In the new study of 60 people with lupus, participants who took 3 grams of
omega-3 polyunsaturated fish oil supplements daily for six months showed
improvements in the symptoms of their disease, as measured by two standard
tools, when compared to their counterparts who received dummy pills.
一项新研究纳入60名狼疮患者,使其每天服用3g ω-3多烯鱼油六个月,通过两种标准
工具进行检测,结果发现与接受安慰剂的对照组相比,服用鱼油组的疾病症状获得改
善。
In addition, the participants who took the fish oil supplements also showed
improved blood vessel function and a reduction in measures of oxidative stress
. Oxidative stress has been linked to heart disease.
另外,服用鱼油的受试者其血管功能也获得改善,氧化应激也减少。而氧化应激与心
脏病有关。
"This study confirms the beneficial effects of omega-3 fish oils in improving
the symptoms of [lupus] and also provides evidence of the potential cardioprotective
effect they may have in this group of patients," researcher Stephen Wright
, MD, a specialist registrar in rheumatology at Queen's University of Belfast
in Northern Ireland, says in a news release.
“该项研究证实了ω-3鱼油对于改善狼疮症状方面的益处,而且也为狼疮患者提供了
潜在的心脏病预防作用,”研究人员北爱尔兰贝尔发斯特皇家学院风湿病学专家Stephen
Wright博士在一次新闻发布会上说。
Aside from being a disease of the immune system, lupus is also a vascular
disease, points out John J. Cush, MD, director of clinical rheumatology at
Baylor Research Institute in Dallas.
狼疮不仅是一种免疫系统疾病,同时也是一种血管疾病,Dallas Baylor 研究所的临
床风湿病学主任John J. Cush博士指出。
"We spend a lot of time talking about the immune system in lupus, but we recognize
there is a very important vascular component to this disease," he says. "
Lupus has cumulative effects on the blood vessels over the years, and this
also needs to be addressed."
“我们花了许多时间讨论狼疮的免疫系统,但是我们发现该疾病对血管有非常重要的
影响,”他说。“狼疮在血管上有经年累月的累积作用,这也需要加以解决。”
Fish oil supplements may help address the blood vessel damage seen in the
disease, he says.
他说,补充鱼油能帮助改善该疾病中所出现的血管损伤。
The new study is "very encouraging and speaks to another way that lupus can
be successfully managed," Cush tells WebMD.
该项新研究是“非常鼓舞人心的,而且提出了成功治愈狼疮的另一种方法,”Cush告
诉WebMD记者。
Cush says the benefits seen in the study are probably not achievable by simply
eating more
fatty fish in the diet because the amount of fish that a person would need
to eat on a regular basis to get 3 grams of omega-3 is too high.
Cush说,研究中所观察到的效果,仅在饮食中多吃脂质鱼可能达不到,因为一个人要
获得3g的ω-3鱼油需要的鱼量太多了。
"Patients with lupus need to control blood pressure, avoid high-fat diets
that are bad for vascular diseases of any kind, and maybe use of omega-3 supplements
," Cush says. "They are fairly cheap and may produce benefits without producing
any harm."
“狼疮患者需要控制血压,避免对血管疾病有害的高脂肪饮食,因此可以补充ω-3鱼
油,” Cush说。“它们相当便宜,带来好处的同时没有一点坏处。”
The bottom line? "This is encouraging information that merits larger study
in larger number of patients over longer time," he says.
基础值?“令人振奋的是,在更长时间更大患者量的研究中优势更明显,”他说。
Remember to tell your rheumatologist about whatever supplements you are taking
, Cush says.
Cush说,记得告诉你的风湿病学家你正在服用什么补充剂。

2007年11月7日波士顿新闻报道,据美国风湿病学会年会上的一项新研究称,补充鱼油
可能会改善狼疮症状。此外,补充鱼油也能改善狼疮患者的血液流动及血管功能,而
该类患者通常患心脏病的风险较高。研究人员北爱尔兰贝尔发斯特皇家学院风湿病学
专家Stephen Wright博士在一次新闻发布会上称,该项研究证实了ω-3鱼油对于改善
狼疮症状方面的益处,而且也为狼疮患者提供了潜在的心脏病预防作用。

狼疮是一种自身免疫性疾病,当身体出现对抗自身组织器官(包括皮肤、关节、肾脏
、大脑、心脏、肺和血液)的轻微炎症时该病发作。据纽约红斑狼疮基金的调查结果
显示,美国约有50万人患此病。

该项新研究纳入60名狼疮患者,使其每天服用3g ω-3多烯鱼油六个月,通过两种标准
工具进行检测,结果发现与接受安慰剂的对照组相比,服用鱼油组的疾病症状获得改
善。另外,服用鱼油的受试者其血管功能也获得改善,而且与心脏病有关的氧化应激
也减少。

Dallas Baylor 研究所的临床风湿病学主任John J. Cush博士指出,狼疮不仅是一种
免疫系统疾病,同时也是一种血管疾病。他说,我们花许多时间讨论狼疮的免疫系统
情况,但我们发现该疾病对血管有非常重要的影响。狼疮在血管上有经年累月的累积
作用,这是需要解决的问题。而补充鱼油有助于改善该疾病中所出现的血管损伤。Cush
对WebMD记者称,该项新研究非常鼓舞人心,而且提出了成功治愈狼疮的另一种方法。
但研究中所观察到的效果,若仅通过饮食中多吃脂质鱼不可能达到,因为一个人要获
得3g的ω-3鱼油需要吃的鱼量太大了。狼疮患者需要控制血压,避免对血管疾病有害
的高脂肪饮食,因此Cush推荐可以补充ω-3鱼油,它们相当便宜,带来好处的同时没
有一点坏处。而且令人振奋的是,在更长时间更大患者量的研究中优势更明显。(丁
香)
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stonyl

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好文摘,谢谢
2楼2007-11-13 11:30:38
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