| 查看: 44 | 回复: 0 | ||
| 当前主题已经存档。 | ||
[资源]
[原创翻译]老年人阻塞性睡眠呼吸暂停与癫痫相关性研究
|
||
|
NEUROLOGY 2007;69:1823-1827 © 2007 American Academy of Neurology Obstructive sleep apnea is associated with seizure occurrence in older adults with epilepsy Background: Although epileptic seizures occur more commonly in older adults, their occurrence in this age group is often unexplained. One unexplored precipitant of seizures in older adults is obstructive sleep apnea (OSA), which is also more common in this age group. Our objective was to investigate whether OSA is associated with seizure exacerbation in older adults with epilepsy. 背景：虽然痫样发作在老年人非常常见，但却难以解释。睡眠呼吸暂停（OSA）也常发生于这一年龄段的老年人。我们研究的目的在于观察二者之间的相关性。 Methods: Polysomnography was performed in older adult patients with late-onset or worsening seizures (Group 1, n = 11) and those who were seizure-free or who had improvement of seizures (Group 2, n = 10). 方法：晚发或加重的老年癫痫患者为一组（组1，n＝11），没有癫痫发作或减轻的老年人为一组（组2，n＝10），分别监测多导睡眠图。 Results: Patients in Group 1 had a significantly higher apnea-hypopnea index than patients in Group 2 (p = 0.002). Group 1 patients also had higher Epworth Sleepiness Scale scores (p = 0.009) and higher scores on the Sleep Apnea Scale of the Sleep Disorders Questionnaire (p = 0.04). The two groups were similar in age, body mass index, neck circumference, number of antiepileptic drugs currently used, and frequency of nocturnal seizures. 结果：组1患者比组2患者的呼吸暂停指数显著增高（p = 0.002）、Epworth嗜睡量表评分增高（p = 0.009）、睡眠障碍问卷的睡眠呼吸暂停评分增高（p = 0.04）。两组在年龄、身体指数、颈部周径、近期抗癫痫药使用数量、夜间发作频率无差异。（奇怪，第2组不是没有癫痫或癫痫好转的患者吗？后面两项怎么会没有差异？） Conclusions: Obstructive sleep apnea is associated with seizure exacerbation in older adults with epilepsy, and its treatment may represent an important avenue for improving seizure control in this population 结论：阻塞性睡眠呼吸暂停与老年性癫痫加重有关，针对阻塞性睡眠呼吸暂停的治疗可能是这一人群进一步控制癫痫发作的一条重要途径。 |
回复此楼» 猜你喜欢
求助Clinical cancer research投稿状态
已经有2人回复
-
请问今年国家自然科学基金申报，是否还需要把代表性论文和获奖证明上传到附件中？
已经有4人回复
-
康复医学论文润色/翻译怎么收费?
已经有201人回复
-
中不中怎么样，在科里生活一样艰难，何况还不中
已经有17人回复
-
请问International Journal of Biological Macromolecules 这个期刊怎么样？
已经有16人回复
-
297临床医学求调剂
已经有0人回复
-
293T-ASC-GFP构建方法，或是已发表过的ASC序列
已经有0人回复
-
请问今年国基申报，参与人有邮件确认环节吗？
已经有3人回复
-
295分调剂
已经有0人回复
-
【招生启事】澳门大学中华医药研究院国家重点实验室招收硕士博士研究生
已经有1人回复
