| 查看: 140 | 回复: 0 | ||
| 当前主题已经存档。 | ||
[资源]
Lipases and Phospholipases in Drug Development
|
||
|
Lipases and Phospholipases in Drug Development: From Biochemistry to Molecular Pharmacology By Günter Müller, Stefan Petry Publisher: Wiley-VCH Number Of Pages: 354 Publication Date: 2004-04-29 ISBN-10 / ASIN: 3527306773 ISBN-13 / EAN: 9783527306770 Binding: Hardcover Lipases and Phospholipases are key control elements in mammalian metabolism. They share many common features that set them apart from other metabolic enzyme classes, most importantly their association with biological membranes. Their potential as drug targets for the treatment of metabolic diseases is widely recognized, and the first lipase inhibitor drugs have been successfully introduced. Providing drug developers with a firm foundation for lipase-centered drug design, the editors of this volume have assembled experts from different scientific disciplines to create a comprehensive handbook for all pharmaceutical chemists, biochemists and physiologists working with lipases. The authors examine fundamental aspects of lipase function in vitro and in vivo, explaining how this knowledge may be used to develop lipase assays. They also treat the physiological roles of lipases in normal and disordered metabolism, as well as strategies to target lipases for the treatment of diabetes, obesity and related disorders. Additional topics include the application of phospholipases for liposome-based drug delivery and their use as diagnostic tools. By Günter Müller, Stefan Petry -------------------------------------------------------------------------------- Publisher: Wiley-VCH Number Of Pages: 354 Publication Date: 2004-04-29 ISBN-10 / ASIN: 3527306773 ISBN-13 / EAN: 9783527306770 Binding: Hardcover -------------------------------------------------------------------------------- Book Description: Lipases and Phospholipases are key control elements in mammalian metabolism. They share many common features that set them apart from other metabolic enzyme classes, most importantly their association with biological membranes. Their potential as drug targets for the treatment of metabolic diseases is widely recognized, and the first lipase inhibitor drugs have been successfully introduced. Providing drug developers with a firm foundation for lipase-centered drug design, the editors of this volume have assembled experts from different scientific disciplines to create a comprehensive handbook for all pharmaceutical chemists, biochemists and physiologists working with lipases. The authors examine fundamental aspects of lipase function in vitro and in vivo, explaining how this knowledge may be used to develop lipase assays. They also treat the physiological roles of lipases in normal and disordered metabolism, as well as strategies to target lipases for the treatment of diabetes, obesity and related disorders. Additional topics include the application of phospholipases for liposome-based drug delivery and their use as diagnostic tools. http://rapidshare.com/files/6694 ... ment_3527306773.rar |
回复此楼» 猜你喜欢
售SCI一区T0P文章，我:8O.55.1.O.5.4,科目齐全,可+急
已经有7人回复
-
售SCI文章，我:8O5.5.1.O.54,科目齐全,可+急
已经有8人回复
-
售SCI一区文章，我:8.O.55.1.O.54,科目齐全,可伽急
已经有7人回复
-
售SCI一区文章，我:8.O.551.O.5.4,科目全,可伽急
已经有8人回复
-
各位基础老师们，看完中央《从严治党》的决定后，对学术界更加有信心了吧
已经有5人回复
-
2027博士申请-临床检验诊断学、病原生物学、微生物方向
已经有5人回复