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bartob123321铜虫 (小有名气)
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[求助]
求助一段论文的中文翻译
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| TopBP1 protein was found in the nuclear fraction of all normal breast tissue samples. Low level of TopBP1 was also detected in cytoplasmic fraction of seven normal tissue specimens. TopBP1 protein was found in all nuclear and one cytoplasmic fraction of analyzed breast cancer in grade I.Pattern of TopBP1 protein expression in well-differentiated breast cancer was similar to normal breast tissue samples. In 10 of 30 moderate differentiated breast cancers expression of TopBP1 was observed only in the nuclear fraction. In the remaining 20 tumor samples in grade II, TopBP1 protein was also detected in cytoplasmic fraction. However, level of this protein was lower in cytoplasmic fraction than nuclear fraction. In the case of four poorly differentiated breast cancer, TopBP1 protein was in the nuclear fraction and was absent in the cytoplasmic fraction. In 6 of 16 breast cancer in grade III, TopBP1 protein was reveals in both the nuclear and cytoplasmic fractions. However, the level of TopBP1 protein in two of these samples was higher in cytoplasmic fraction than in the nuclear fraction. |
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