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[电子图书]Medicinal Mushrooms:
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Medicinal Mushrooms: Their therapeutic properties and current medical usage with special emphasis on cancer treatments By NEIL J ROWAN, JOHN E SMITH and RICHARD SULLIVAN Introduction Many of the currently available anti-cancer agents are derived form natural products, for instance paclitaxel (Taxol), and camptothecin (Hycamtin) amongst many others. In 2000 Professor Gordon McVie, Director-General of the Cancer Research Campaign (now Cancer Research UK) and Professor John Smith of University of Strathclyde met in Glasgow to discuss the role of medicinal mushrooms in the treatment of cancer. The CRC had become aware that these natural products were being used extensively in the Far East as nutriceuticals (dietary supplements) and as a source for the generation of pharmaceutical-grade medicines to treat a wide variety of diseases, including cancer. The substantial range of medicinal mushroom species from which different bioactive compounds can be derived suggested that the humble mushroom could be a source of novel anti-cancer agents. This monograph is a comprehensive overview of this subject from the technology of cultivation, extraction and chemistry of medicinal mushroom bioactive compounds to the clinical evidence that suggests an important therapeutic role in cancer, and other major diseases. Index Bibliographies Acknowledgements Preamble Page (i)-(iv) Executive Summary A-I Chapter 1: Introduction 1 Chapter 2: The nature of fungi with special emphasis on mushrooms 11 Chapter 3: Medicinally important mushrooms 24 Chapter 4: Technology of mushroom cultivation 64 Chapter 5: Extraction, development and chemistry of anti-cancer compounds from medicinal mushrooms 80 Chapter 6: Immunomodulatory activities of mushroom glucans and polysaccharide-protein complexes in animals and humans 106 Chapter 7: The role of polysaccharides derived from medicinal mushrooms in cancer 142 Chapter 8: Additional medicinal properties 180 Chapter 9: Regulatory and safety criteria for functional foods and dietary supplements and pharmaceutical medicines: the role for medicinal mushrooms 201 Chapter 10: Conclusions 220 Appendix 1: Overview of the human immune system 235 Appendix 2: Standard antitumour activity test in Sarcoma 180/mice 251 Appenidx 3: Medicinal mushrooms and cancer chemoprevention 253 http://www.91files.com/?WJ928OPW57RQWZIRW41Z |
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