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[×ÊÔ´] Fundamentals of Psychopharmacology

Fundamentals of Psychopharmacology
By Brian E. Leonard
Publisher:  Wiley
Number Of Pages:  536
Publication Date:  2003-11-14  
ISBN / ASIN:  0471521787


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Book Description:

Treatment with drugs is fundamental to modern therapy of psychiatric disorders. The number of disorders responsive to drug treatment is increasing, reflecting the extensive synthesis of novel compounds and the greater understanding of the aetiology of the disorders.

This third edition provides new and updated material, including an additional chapter on clinical trials and their importance in assessing the efficacy and safety of psychotropic drugs. As molecular biology and imaging techniques are of increasing importance to basic and clinical neuroscience, these areas have also been extended to illustrate their relevance to our understanding of psychopharmacology.

This book is essential reading for undergraduates in pharmacology and the neurosciences, postgraduate neuropharmacologists, psychiatrists in training and in practice and medical researchers.

Reviews of the Second Edition

"¡­this text is eminently readable, well researched, and probably the best of its kind.

The book is well worth buying and anyone who claims to know anything about psychopharmacology will be expected to have a heavily annotated copy." Irish Journal of Psychological Medicine

"¡­[this is] a very good book, especially suited to those interested in psychopharmacologic research and psychiatric residency in training." Journal of Chemical Neuroanatomy


Preface to Third Edition ix
Preface to Second Edition xi
Preface to First Edition xiii
Introduction xv
1 Functional Neuroanatomy of the Brain 1
2 Basic Aspects of Neurotransmitter Function 15
3 Pharmacokinetic Aspects of Psychopharmacology 79
4 Clinical Trials and their Importance in Assessing the Efficacy
and Safety of Psychotropic Drugs 101
5 Molecular Genetics and Psychopharmacology 113
6 Psychotropic Drugs that Modify the Serotonergic System 133
7 Drug Treatment of Depression 153
8 Drug Treatment of Mania 193
9 Anxiolytics and the Treatment of Anxiety Disorders 211
10 Drug Treatment of Insomnia 241
11 Drug Treatment of Schizophrenia and the Psychoses 255
12 Drug Treatment of the Epilepsies 295
13 Drug Treatment of Parkinson¡¯s Disease 319
14 Alzheimer¡¯s Disease and Stroke: Possible Biochemical Causes
and Treatment Strategies 341
15 Psychopharmacology of Drugs of Abuse 375
16 Paediatric Psychopharmacology 417
17 Geriatric Psychopharmacology 425
18 The Inter-relationship Between Psychopharmacology and
Psychoneuroimmunology 431
19 Endocoids and their Importance in Psychopharmacology 445
Appendix 1 Some Important Psychotropic Drug Interactions 459
Appendix 2 Glossary of some Common Terms Used
in Psychopharmacology 463
Appendix 3 Generic and Proprietary Names of Some
Common Psychotropic Drugs 483
Appendix 4 Key References for Further Reading 489
Index 499
viii CONTENTS
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