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Chemical Society Reviews最新综述：共轭聚合物-纳米粒子的合成。性质及其应用
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由于共轭聚合物与纳米粒子之间的相互作用，共轭聚合物纳米粒子（CPNs）被广泛应用于催化，传感器，生物，电池等领域。本综述详细介绍了CPNs的制备，性质，功能化及其应用。文章对相关研究者来说具有重要的参考价值。 In the past few years, conjugated polymer nanoparticles (CPNs) have been successfully prepared and applied in the biological field because of their unique opto-electronic properties. The rapid development of CPNs is mainly attributed to their simple synthesis procedures and easy separation steps. The advantages of CPNs include high brightness, excellent photostability, low cytotoxicity, high quantum yield and versatile surface modification. The functionalization of CPNs with specific recognition elements imparts them good ability for targeted recognition and imaging in vitro and in vivo. CPNs can be applied to deliver drug and gene, and simultaneously to real-time monitor the release process due to their self-luminous characteristics. Moreover, CPNs can sensitize oxygen molecules to generate reactive oxygen species (ROS) which can kill adjacent bacteria and tumor cells. In this tutorial review, we provide a recent development of the preparation methods, properties, and functionalization strategies of CPNs, especially discussing their biological applications in targeted imaging, drug/gene delivery and biomedicine. The challenges and outlooks in this field will also be discussed. |
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130楼2014-06-15 07:01:25
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2013-06-07 22:04
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2013-06-08 06:39
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2013-06-08 08:44
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2013-06-08 08:47
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2013-06-08 09:02
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2013-06-08 11:16
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2013-06-08 11:16
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2013-06-08 12:15
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2013-06-08 14:49
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