| 查看: 157 | 回复: 3 | |||
| 【奖励】 本帖被评价2次，作者lihai0910增加金币 1.5 个 | |||
| 当前主题已经存档。 | |||
[资源]
Functional Informatics in Drug Discovery
|
|||
|
Functional Informatics in Drug Discovery By Sergey Ilyin Publisher: CRC Number Of Pages: 160 Publication Date: 2007-08-21 Sales Rank: 974496 ISBN / ASIN: 1574444662 EAN: 9781574444667 Binding: Hardcover Manufacturer: CRC Studio: CRC Average Rating: Total Reviews: -------------------------------------------------------------------------------- Book Description: Integrating various technologies with informational systems provides vast improvements to the overall research and development that occur in the biopharmaceutical industry. One of the first books to explore this area, Functional Informatics in Drug Discovery examines all aspects of technology integration and information flow in a biopharmaceutical enterprise and outlines the specific technologies used at various stages of drug development. With contributions from leaders in academia, information technology, and the pharmaceutical industry, each chapter illustrates how a particular area of biological science can benefit from the tools of informatics. The book first looks at intelligent automation, neurally based computational tools, and pharmacodynamic (PD) biomarkers. It then reviews a variety of novel technologies and approaches presently used in drug discovery at Johnson & Johnson. The text also describes how informatics can advance antibody technology and drug development for oncology. After focusing on forward genetic and reverse genetic strategies to identify relevant target genes for drug discovery, the book explains proteomic expression profiling and explores the application of laser microdissection in transcriptomics. Taking a systematic approach, this volume examines the impact of informatics tools on various areas in biopharmaceuticals by presenting in-depth analyses of emerging trends and future opportunities. Preface......................................................................................................................vii Editor.........................................................................................................................ix Contributors ..............................................................................................................xi Chapter 1 Intelligent Automation .........................................................................1 James M. Dixon Chapter 2 Neurally Inspired Algorithms as Computational Tools.....................13 Mark Flynn and Garrett T. Kenyon Chapter 3 Using Pharmacodynamic Biomarkers to Accelerate Early Clinical Drug Development ...........41 Ole Vesterqvist Chapter 4 Opportunities in CNS Drug Discovery and Development................55 Albert Pinhasov, Anil H. Vaidya, Hong Xin, Daniel Horowitz, Daniel Rosenthal, Douglas E. Brenneman, Ewa Malatynska, Sergey E. Ilyin, and Carlos R. Plata-Salamán Chapter 5 Clinical Success of Antibody Therapeutics in Oncology .................65 Bernard J. Scallon, Linda A. Snyder, G. Mark Anderson, Qiming Chen, Li Yan, and Marian T. Nakada Chapter 6 Relating Target Sequence to Biological Function.............................91 Greg M. Arndt Chapter 7 Use of Protein Microarrays for Molecular Network Analysis and Signal-Pathway Profiling ......115 Katherine R. Calvo, Lance A. Liotta, and Emanuel F. Petricoin Chapter 8 Laser-Microdissection-Based Transcriptomics Using Microarrays ....131 Fredrik Kamme, Bernd Meurers, Jessica Zhu, Da-Thao Tran, Jingxue Yu, Changlu Liu, Andrew Carmen, and Bingren Hu Index.................................................141 http://www.91files.com/?HTE7NTLSQ2MPT93IOWU1 |
回复此楼» 猜你喜欢
求助一下有机合成大神
已经有4人回复
-
拟解决的关键科学问题还要不要写
已经有8人回复
-
请教限项目规定
已经有5人回复
-
最失望的一年
已经有16人回复
-
存款400万可以在学校里躺平吗
已经有33人回复
-
求推荐英文EI期刊
已经有5人回复
-
26申博
已经有3人回复
-
基金委咋了？2026年的指南还没有出来？
已经有10人回复
-
基金申报
已经有6人回复
-
疑惑？
已经有5人回复
2楼2007-10-10 11:54:49