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Absorption and Drug Development: Solubility, Permeability, and Charge State
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Many times drugs work fine when tested outside the body, but when they are tested in the body they fail. One of the major reasons a drug fails is that it cannot be absorb by the body in a way to have the effect it was intended to have. Permeability, Solubility, Dissolution, and Charged State of Ionizable Molecules: * Helps drug discovery professionals to eliminate poorly absorbable molecules early in the drug discovery process, which can save drug companies millions of dollars. * Extensive tabulations, in appendix format, of properties and structures of about 200 standard drug molecules. http://www.divshare.com/download/2270829-d68 |
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2楼2007-10-10 10:36:43
3楼2007-10-10 17:25:29
