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Farnesyltransferase Inhibitors in Cancer Therapy
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Farnesyltransferase Inhibitors in Cancer Therapy (Cancer Drug Discovery and Development) Publisher: Humana Press Number Of Pages: 280 Publication Date: 2001-01-15 Cutting-edge researchers describe their efforts to design, synthesize, and evaluate the biological activities of farensyltransferase inhibitors (FTIs); geranylgeranyltransferase read.freeduan.com inhibitors (GGTIs) are also discussed as potential anticancer drugs. The authors survey in detail such inhibitors as CAAX box peptidomimetics, FPP mimics, and bisubstrate transition state analogs, and critically review their uses in combination with radiation and other cytotoxic agents, such as gemcitabine, cisplatin, and taxanes. Illuminating and richly detailed, Farnesyltransferase Inhibitors in Cancer Therapy constitutes today's standard reference for the pathbreaking use of FTIs and GGTIs in anticancer therapy and offers basic and clinical investigators a comprehensive treatment of the scientific and medical aspects of farnesyltransferase inhibitors. [ Last edited by msd2phd on 2007-10-9 at 09:03 ] |
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2楼2007-10-06 19:46:56
3楼2007-10-08 20:44:54