24小时热门版块排行榜

>论坛更新日志 (4723)
>导师招生 (1004)
>文献求助 (341)
>考研 (329)
>虫友互识 (294)
>硕博家园 (285)
>招聘信息布告栏 (274)
>考博 (238)
>博后之家 (225)
>生物材料 (143)
>找工作 (129)
>海外博后 (112)
>休闲灌水 (58)
>论文投稿 (47)
>基金申请 (37)
>教师之家 (32)

返回列表

【奖励】本帖被评价10次，作者msd2phd增加金币 9 个

当前主题已经存档。

当前只显示满足指定条件的回帖，点击这里查看本话题的所有回帖

msd2phd

至尊木虫 (职业作家)

应助: 0 (幼儿园)
贵宾: 0.1
金币: 22077.4
帖子: 4713
在线: 133.9小时
虫号: 88003

[资源] Computational Toxicology

Computational Toxicology: Risk Assessment for Pharmaceutical and Environmental Chemicals (Wiley Series on Technologies for the Pharmaceutical Industry)

# Publisher: Wiley-Interscience
# Number Of Pages: 814
# Publication Date: 2007-06-29

A comprehensive analysis of state-of-the-art molecular modeling approaches and strategies applied to risk assessment for pharmaceutical and environmental chemicals

This unique volume describes how the interaction of molecules with toxicologically relevant targets can be predicted using computer-based tools utilizing X-ray crystal structures or homology, receptor, pharmacophore, and quantitative structure activity relationship (QSAR) models of human proteins. It covers the in vitro models used, newer technologies, and regulatory aspects. The book offers a complete systems perspective to risk assessment prediction, discussing experimental and computational approaches in detail, with:

*

   An introduction to toxicology methods and an explanation of computational methods
*

   In-depth reviews of QSAR methods applied to enzymes, transporters, nuclear receptors, and ion channels
*

   Sections on applying computers to toxicology assessment in the pharmaceutical industry and in the environmental arena
*

   Chapters written by leading international experts
*

   Figures that illustrate computational models and references for further information

This is a key resource for toxicologists and scientists in the pharmaceutical industry and environmental sciences as well as researchers involved in ADMET, drug discovery, and technology and software development.
http://rapidshare.com/files/56360084/Ekin9780470049624.rar

回复此楼