24小时热门版块排行榜

返回列表

【奖励】本帖被评价21次，作者lihai0910增加金币 16.5 个

当前主题已经存档。

当前只显示满足指定条件的回帖，点击这里查看本话题的所有回帖

lihai0910

至尊木虫 (著名写手)

应助: 22 (小学生)
金币: 26551.1
帖子: 2327
在线: 110小时
虫号: 226499

[资源] [电子书] LC/MS Applications in Drug Development全书下载

Mike S. Lee
Wiley (March 2002)
ISBN: 978-0-471-40520-7
Hardcover
256 pages

Breakthroughs in combinatorial chemistry and molecular biology, as well as an overall industry trend toward accelerated development, mean the rate of sample generation now far exceeds the rate of sample analysis in the pursuit of producing new and better pharmaceuticals. LC/MS is an analytical tool that helps the researcher identify the most promising sample early in the selection process, effectively creating a shortcut to finding new drugs. This book is the first to describe LC/MS applications within the context of drug development, including the discovery, preclinical, clinical, and manufacturing phases.
In addition to the thorough technical analysis of this tool, LC/MS Applications in Drug Development provides perspective on the significant changes in strategies for pharmaceutical analysis. A process overview of drug development from an analytical point of view is provided along with essential data required to successfully bring a drug to market. The incorporation of LC/MS is illustrated from target to product. Chapters pertaining to the discovery process itself include:
Proteomics
Glycoprotein Mapping
Natural Products Dereplication
Lead Identification Screening
Open-Access LC/MS
In Vitro Drug Screening
Written for both the analytical chemist who uses LC/MS applications and the pharmaceutical scientist who works with the drugs they produce, LC/MS Applications in Drug Development is the premier reference on the subject.

Table of Contents:
Preface.
Acknowledgments.

Introduction.

Drug Development Overview.

Accelerated Drug Development.

LC/MS Development.

LC/MS Applications.

Future Applications and Prospects.

Perspectives on the Future Growth of LC/MS.

Conclusions.

Glossary.

References.

Index.

回复此楼