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Retraction
WE WISH TO RETRACT OUR REPORT ¡°CDX2 GENE EXPRESSION AND TROPHECTODERM
LINEAGE
specification in mouse embryos¡± (1). Allegations of research misconduct
were received by the
University of Missouri-Columbia (MU) Provost, and an investigation found
that the first author
(K.D.) engaged in research misconduct by intentionally falsifying and
fabricating digital
images in the preparation of Figs. 4I; 4N; 4S; 2G; 3, J to L; S2, V to X;
and S6, I to K accompanying
the Science article. In addition, the original raw image files for the
majority of the figures
in the paper have not been located (the exceptions being the confocal
scanning images in
Figs. S1, S3, S4, S5, and S6), raising the possibility that the data they
represent may also be
suspect. We have decided to withdraw the article in its entirety in view of
the fact that the paper
was founded at least in part on falsified or fabricated images.
The corresponding author (R.M.R.) takes responsibility for placing excessive
trust in his coworker
and for not assuring that a complete set of raw data existed at the time the
questions first
arose about the paper. We deeply regret any scientific misconceptions that
have resulted from
the publication of this article.
The first author resigned from MU shortly after the allegations of research
misconduct were
received and could not be found to sign the retraction.
R. MICHAEL ROBERTS,1 M. SIVAGURU,2 H. Y. YONG3
1Division of Animal Sciences, University of Missouri, Columbia, MO 65211,
USA. 2Institute for Genomic Biology, University
of Illinois, Urbana-Champaign, IL 61801, USA. 3BK21 Dental Research
Institute, College of Dentistry, Seoul National
University, 28 Yongun-dong, Chongno-gu, Seoul 110-749, Korea.
Reference
1. K. Deb, M. Sivaguru, H. Y. Yong, R. M. Roberts, Science 311, 992 (2006).
Editor¡¯s Note: Science published an Editorial Expression of Concern (27
October 2006,
p. 592) about this paper, which alerted readers to the then-ongoing
investigation.
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