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compound 1 exhibited a moderately slow off-rate, leading to a so-called ¡°pseudo-irreversible¡± (PI) profile from the intracellular kinasedomains of HER2 and EGFR. ÌØ±ðÊÇslow off-rateºÍ¡°pseudo-irreversible¡± (PI) profile·ÒëҪ׼ȷ£¡Ð»Ð»£¡ |
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yuesenior
½ð³æ (ÕýʽдÊÖ)
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- ·ÒëEPI: 35
- Ó¦Öú: 4 (Ó×¶ùÔ°)
- ½ð±Ò: 1794.7
- É¢½ð: 61
- ºì»¨: 20
- Ìû×Ó: 350
- ÔÚÏß: 111.3Сʱ
- ³æºÅ: 2245490
- ×¢²á: 2013-01-17
- רҵ: ÖÊÆ×·ÖÎö

2Â¥2013-03-08 23:57:18
496092102
Òø³æ (СÓÐÃûÆø)
- ·ÒëEPI: 1
- Ó¦Öú: 1 (Ó×¶ùÔ°)
- ½ð±Ò: 456.2
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- ³æºÅ: 1894123
- ×¢²á: 2012-07-15
- ÐÔ±ð: GG
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phu_grassman: ½ð±Ò+1, thanks and welcome here to share your opinions. 2013-03-10 09:34:50
zhangy473: ½ð±Ò+5, ·ÒëEPI+1, ¡ï¡ï¡ï¡ï¡ï×î¼Ñ´ð°¸, лл£¡ 2013-03-11 09:11:00
phu_grassman: ½ð±Ò+1, thanks and welcome here to share your opinions. 2013-03-10 09:34:50
zhangy473: ½ð±Ò+5, ·ÒëEPI+1, ¡ï¡ï¡ï¡ï¡ï×î¼Ñ´ð°¸, лл£¡ 2013-03-11 09:11:00
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a moderately slow off-rate Ò»¸ö±È½ÏÂýµÄ½âÀëËÙÂÊ ¡°pseudo-irreversible¡± (PI) ¡°Î±²»¿ÉÄæ×ª¡± £¨PI£© |
3Â¥2013-03-09 20:43:11













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