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2013年新著——DNA复制机理（英文版）
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"The Mechanisms of DNA Replication" ed. by David Stuart InTeOpP | 2013 | ISBN: 9535109914 9789535109914 | 496 pages | PDF | 19 MB The chapters in this volume outline and review the current state of knowledge on several key aspects of the DNA replication process. The reader will be provided with new insights into the initiation, regulation, and progression of DNA replication as well as a collection of thought provoking questions and summaries to direct future investigations. DNA replication is a fundamental part of the life cycle of all organisms. Not surprisingly many aspects of this process display profound conservation across organisms in all domains of life. Contents Preface Section 1 Machines that Drive DNA Replication 1 Pulling the Trigger to Fire Origins of DNA Replication 2 Replicative Helicases as the Central Organizing Motor Proteins in the Molecular Machines of the Elongating Eukaryotic Replication Fork 3 The MCM and RecQ Helicase Families: Ancient Roles in DNA Replication and Genomic Stability Lead to Distinct Roles in Human Disease 4 DNA Replication in Archaea, the Third Domain of Life 5 Proposal for a Minimal DNAAuto-Replicative System 6 Extending the Interaction Repertoire of FHAand BRCT Domains 7 Intrinsically Disoredered Proteins in Replication Process Section 2 Mechanisms that Protect Chromosome Integrity During DNA Replication 8 Preserving the Replication Fork in Response to Nucleotide Starvation: Evading the Replication Fork Collapse Point 9 The Role of WRN Helicase/Exonuclease in DNA Replication Section 3 Replication of Organellar Chromosomes 10 Replicational Mutation Gradients, Dipole Moments. Nearest Neighbour Effects and DNA Polymerase Gamma Fidelity in Human Mitochondrial Genomes 11 The Plant and Protist Organellar DNA Replication Enzyme POP Showing Up in Place of DNA Polymerase Gamma May Be a Suitable Antiprotozoal Drug Target Section 4 Chromatin and Epigenetic Influences on DNA Replication 12 Roles of Methylation and Sequestration in the Mechanisms of DNA Replication in some Members of the Enterobacteriaceae Family 13 The Mechanisms of Epigenetic Modifications During DNA Replication 14 Chromatin Damage Patterns Shift According to Eu/Heterochromatin Replication 15 A Histone Cycle 16 Replicating - DNA in the Refractory Chromatin Environment Section 5 Telomeres 17 Telomeres: Their Structure and Maintenance 18 Telomere Shortening Mechanisms  InTeOpP | 2013 | ISBN: 9535109914 9789535109914 | 496 pages | PDF | 19 MB [ Last edited by Pureland on 2013-2-21 at 12:22 ] |
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