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yin198716

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An explanation of the contrasting actions of Jag1 and Dll4 has been provided, on the basis of the observation of competition of the pro-angiogenic Jag1 with the angiogenic suppressor of Dll4.This was demonstrated in the mouse retina and HUVECs in vitro and depended on the effect of Manic Fringe or other Fringes on glycosylation of Notch.
Oncology
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