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yin198716

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1 Notably, chronic DLL4 blockade in male rats resulted in a dose-dependent increase in ulcerating, subcutaneous tumours that were typically well circumscribed and displayed focally infiltrating borders .

2Most areas of the tumours were cellular with some regions demonstrating central areas of necrosis. At higher power, tumours had features of vascular neoplasms with cellular components interdigitated with irregularly shaped blood vessels of varying sizes .
Oncology
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zjpa

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sltmac: 金币+1 2013-01-19 08:45:33
sltmac: 欢迎常来本版交流 2013-01-19 08:45:43
yin198716: 金币+2, 翻译EPI+1, 有帮助 2013-01-21 14:09:44
phu_grassman: 金币+3, thanks. 2013-03-02 12:19:46
1.值得注意的是,雄性大鼠慢性DLL4阻滞导致溃疡性皮下肿瘤呈剂量依赖性增加,皮下肿瘤通常边界清楚,且显示灶性浸润性边界。
2.大面积肿瘤的细胞表现为部分区域显示中心区坏死。在更高倍镜显微镜下观察,肿瘤具有血管肿瘤特性,细胞成分与大小不等的不规则形血管互相交叉。
tryandjusttry
2楼2013-01-18 23:38:10
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